TSLP Antibody (152614)

Images

 
Recombinant Mouse TSLP (Catalog # 555-TS) stimulates proliferation in the BaF3 mouse pro‑B cell line transfected with mouse IL‑7 R alpha in a dose-dependent manner (orange line). Proliferation ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, B/N
Clone
152614
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated

Order Details

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Catalog# & Formulation Size Price

TSLP Antibody (152614) Summary

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse TSLP
Tyr20-Glu140
Accession # Q9JIE6
Specificity
Detects mouse TSLP in Western blots.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
TSLP
Purity
Protein A or G purified from hybridoma culture supernatant
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Endotoxin Note
<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
  • Neutralization 0.1-0.4 ug/mL
Publications
Read Publications using
MAB555 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TSLP Antibody (152614)

  • thymic stromal lymphopoietin
  • TSLP

Background

TSLP is an IL-7 related cytokine secreted by multiple tissues. It interacts with the heterodimeric receptor complex consisting of IL-7 R alpha and TSLP R. Mouse TSLP stimulates the growth of thymocytes and mature T cells and also supports B cell lymphopoiesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TSLP Antibody (MAB555)(16)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 6 applications: Flow Cytometry, ICC, IHC, In Vivo, Neutralization, Neutralizing.


Filter By Application
Flow Cytometry
(1)
ICC
(1)
IHC
(1)
In Vivo
(1)
Neutralization
(10)
Neutralizing
(1)
All Applications
Filter By Species
Mouse
(16)
All Species
Showing Publications 1 - 10 of 16. Show All 16 Publications.
Publications using MAB555 Applications Species
S Li, Z Yi, M Deng, MJ Scott, C Yang, W Li, Z Lei, NM Santerre, P Loughran, TR Billiar TSLP protects against liver I/R injury via activation of the PI3K/Akt pathway JCI Insight, 2019;4(22):. 2019 [PMID: 31723054] (Mouse) Mouse
NR Han, PD Moon, HM Kim, HJ Jeong TSLP Exacerbates Septic Inflammation via Murine Double Minute 2 (MDM2) Signaling Pathway J Clin Med, 2019;8(9):. 2019 [PMID: 31480519] (Neutralizing, Mouse) Neutralizing Mouse
Verma M, Liu S, Michalec L, Sripada A, Gorska M, Alam R Experimental asthma persists in IL-33 receptor knockout mice because of the emergence of thymic stromal lymphopoietin-driven IL-9&lt;sup&gt;+&lt;/sup&gt; and IL-13&lt;sup&gt;+&lt;/sup&gt; type 2 innate lymphoid cell subpopulations. J Allergy Clin Immunol, 0;0(0):. 0 [PMID: 29132961] (Neutralization, Mouse) Neutralization Mouse
Y Cao, E Zhang, J Yang, Y Yang, J Yu, Y Xiao, W Li, D Zhou, Y Li, B Zhao, H Yan, M Lu, M Zhong, H Yan Frontline Science: Nasal epithelial GM-CSF contributes to TLR5-mediated modulation of airway dendritic cells and subsequent IgA response J. Leukoc. Biol., 2017;0(0):. 2017 [PMID: 28522600] (Neutralization, Mouse) Neutralization Mouse
Critical role of TSLP-responsive mucosal dendritic cells in the induction of nasal antigen-specific IgA response Mucosal Immunol, 2016;0(0):. 2016 [PMID: 27924821] (Neutralization, Mouse) Neutralization Mouse
Thymic Stromal Lymphopoietin Neutralization Inhibits the Immune Adjuvant Effect of Di-(2-Ethylhexyl) Phthalate in Balb/c Mouse Asthma Model PLoS ONE, 2016;11(7):e0159479. 2016 [PMID: 27467143] (Neutralization, Mouse) Neutralization Mouse
Yu M, Owens D, Ghosh S, Farber D Conditional PDK1 Ablation Promotes Epidermal and T-Cell-Mediated Dysfunctions Leading to Inflammatory Skin Disease. J Invest Dermatol, 2015;135(11):2688-96. 2015 [PMID: 26099023] (IHC, Mouse) IHC Mouse
Cipolat S, Hoste E, Natsuga K, Quist S, Watt F Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility. Elife, 2014;3(0):e01888. 2014 [PMID: 24843010] (In Vivo, Mouse) In Vivo Mouse
Taniguchi K, Arima K, Masuoka M, Ohta S, Shiraishi H, Ontsuka K, Suzuki S, Inamitsu M, Yamamoto K, Simmons O, Toda S, Conway S, Hamasaki Y, Izuhara K Periostin controls keratinocyte proliferation and differentiation by interacting with the paracrine IL-1alpha/IL-6 loop. J Invest Dermatol, 2014;134(5):1295-304. 2014 [PMID: 24352037] (Neutralization, Mouse) Neutralization Mouse
Oh MH, Oh SY, Yu J IL-13 induces skin fibrosis in atopic dermatitis by thymic stromal lymphopoietin. J. Immunol., 2011;186(12):7232-42. 2011 [PMID: 21576506] (Neutralization, Mouse) Neutralization Mouse
Show All 16 Publications.

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Bioinformatics

Gene Symbol TSLP
Uniprot