Rabbit TRF-1 ELISA Kit (Colorimetric)

Product Discontinued

Rabbit TRF-1 ELISA Kit (Colorimetric) Summary

• Description: TRF (Rabbit) ELISA Kit is a highly sensitive two-site enzyme-linked immunoassay for the quantitative determination of TRF in rabbit serum or plasma.
• Standard Curve Range: 3.125 to 100 ng/mL
• Sensitivity: 1.239
• Assay Type: Two-site enzyme-linked immunoassay
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: TERF1

Applications/Dilutions

• Dilutions:
  • ELISA
  • Quantification
• Application Notes: Useful for quantification.

Packaging, Storage & Formulations

• Storage: Store at 4C.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Rabbit TRF-1 ELISA Kit (Colorimetric)

• NIMA-interacting protein 2
• PIN-2
• PIN2hTRF1-AS
• Telomeric protein Pin2/TRF1
• telomeric repeat binding factor (NIMA-interacting) 1
• telomeric repeat binding factor 1
• telomeric repeat binding protein 1
• telomeric repeat-binding factor 1
• TERF1
• TRBF1
• TRF1
• TRF-1
• TRF1FLJ41416
• TRFt-TRF1
• TTAGGG repeat-binding factor 1

Background

Telomeric repeat binding factor 1 (TRF1, TERF1, PIN2, TRBF1) and telomeric repeat binding factor 2 (TRF2, TERF2, TRBF2) are present at telomeres throughout the cell cycle, where they regulate telomerase by acting in cis to limit the elongation of individual chromosome ends. Telomerase adds hexameric repeats of TTAGGG to the ends of chromosomal DNA. This telomerase enzyme plays an influential role in cellular immortalization and cellular senescence. TRF1 negatively regulates telomere elongation, while TRF2 protects the chromosome ends by inhibiting end-to-end fusions. Downregulation of TRF expression in tumor cells may contribute to cell immortalization and malignant progression. TRF1 has an acidic N-terminus while TRF2 has a basic N-terminus. TRF2 localizes in the nucleolus at G0 and S and diffuses out of the nucleolus in G2 phase. During mitosis TRF2 disperses from the condensed chromosomes and returns to the nucleolus at cytokinesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

FAQs for TRF-1 ELISA Kit (KA1977). (Showing 1 - 1 of 1 FAQ).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: TERF1