TRANCE/TNFSF11/RANK L Antibody (88227) [Unconjugated]

• Reactivity: Mu
• Applications: WB
• Clone: 88227
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated

TRANCE/TNFSF11/RANK L Antibody (88227) [Unconjugated] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse TRANCE
  Arg72-Asp316
  Accession # O35235
• Specificity: Detects mouse TRANCE in direct ELISAs and Western blots. In direct ELISAs, shows 100% cross-reactivity with recombinant human (rh) TRANCE and no cross-reactivity with rhAPRIL, rhBAFF, rhCD27 Ligand, recombinant mouse (rm) CD27 Ligand, rhCD30 Ligand, rmCD30 Ligand, rhCD40 Ligand, rmEDA, rhFas Ligand, rmFas Ligand, rhGITR Ligand, rhTNF-alpha , rhTRAK, rmTSG, recombinant cotton rat TNF‑ alpha , rmTNF-alpha , recombinant porcine TNF-alpha , recombinant rat TNF-alpha , and rhVEGI.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: TNFSF11
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TRANCE/TNFSF11/RANK L Antibody (88227) [Unconjugated]

• CD254 antigen
• CD254
• ODF
• OPGL
• OPGLOPTB2
• Osteoclast differentiation factor
• Osteoprotegerin ligand
• RANK L
• RANKL
• RANKLreceptor activator of nuclear factor kappa B ligand
• Receptor activator of nuclear factor kappa-B ligand
• sOdf
• TNF-related activation-induced cytokine
• TNFSF11
• TRANCE
• TRANCEODFhRANKL2
• tumor necrosis factor (ligand) superfamily, member 11
• tumor necrosis factor ligand superfamily member 11

Background

TRANCE, also known as RANK Ligand, is a type II transmembrane protein belonging to the tumor necrosis factor superfamily and has been designated TNFSF11.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TRANCE/TNFSF11/RANK L Antibody (MAB462)(1)

Publication using MAB462

• Islam S, Hassan F, Tumurkhuu G, Dagvadorj J, Koide N, Naiki Y, Mori I, Yoshida T, Yokochi T Bacterial lipopolysaccharide induces osteoclast formation in RAW 264.7 macrophage cells. Biochem. Biophys. Res. Commun., 2007-06-12;360(2):346-51. 2007-06-12 [PMID: 17597583] (Western Blot, Mouse)

Bioinformatics

• Gene Symbol: TNFSF11
• Uniprot:
  • O35235()