TRANCE/TNFSF11/RANK L Products

Antibodies
TRANCE/TNFSF11/RANK L Antibod ...
TRANCE/TNFSF11/RANK L Antibody
AF462
Species: Mu
Applications: WB, IHC, B/N, ELISA(Cap)
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
Antibody Pairs
TRANCE/TNFSF11/RANK L Antibod ...
TRANCE/TNFSF11/RANK L Antibody Pai...
NBP2-79357
Species: Hu
Applications: S-ELISA
Host: Rabbit Monoclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
Mouse TRANCE/RANK L/TNFSF11 Q ...
Mouse TRANCE/RANK L/TNFSF11 Quanti...
MTR00
Species: Mu
Applications: ELISA
Human TRANCE/RANK L/TNFSF11 D ...
Human TRANCE/RANK L/TNFSF11 DuoSet...
DY626
Species: Hu
Applications: ELISA
Mouse TRANCE/RANK L/TNFSF11 D ...
Mouse TRANCE/RANK L/TNFSF11 DuoSet...
DY462
Species: Mu
Applications: ELISA
Lysates
TRANCE/TNFSF11/RANK L Overexp ...
TRANCE/TNFSF11/RANK L Overexpressi...
NBL1-17162
Species: Hu
Applications: WB
TRANCE/TNFSF11/RANK L Overexp ...
TRANCE/TNFSF11/RANK L Overexpressi...
NBL1-17163
Species: Hu
Applications: WB
Proteins
Recombinant Mouse TRANCE/RANK ...
Recombinant Mouse TRANCE/RANK L/TN...
462-TR
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human TRANCE/RANK ...
Recombinant Human TRANCE/RANK L/TN...
6449-TEC
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Mouse TRANCE/RANK ...
Recombinant Mouse TRANCE/RANK L/TN...
462-TEC
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  

Description

TRANCE/OPGL/RANKL/ODF is a recently identified member of tumor necrosis factor family. TRANCE (TNF-related activation-induced cytokine receptor) or RANKL {receptor activator of NF-kB (RANK) ligand} has been implicated in interactions between T cells and dendritic cells (1-2). RANK ligand (RANKL/TRANCE) binds to RANK on dendritic cells, upregulates the expression of anti-apoptotic protein BcL-XL suggesting a role in dendritic cell survival (2). TRANCE/RANKL is also important in T and B-cell maturation (3). As OPGL/ODF (Osteoprotegerin Ligand/Osteoclast differentiation factor), the same protein can both activate mature osteoclasts and mediate osteoclastogenesis (4). OPGL/TRANCE deficient mice show severe osteoporesis and complete absence of osteoclasts as a result of lack of osteogenesis (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 8600
Alternate Names
  • Receptor activator of nuclear factor kappa-B ligand
  • CD254 antigen
  • Osteoprotegerin ligand
  • tumor necrosis factor ligand superfamily member 11
  • Osteoclast differentiation factor
  • sOdf
  • CD254
  • RANKLreceptor activator of nuclear factor kappa B ligand
  • TRANCEODFhRANKL2
  • OPGLOPTB2
  • TNF-related activation-induced cytokine
  • tumor necrosis factor (ligand) superfamily, member 11

Research Areas for TRANCE/TNFSF11/RANK L

Find related products by research area and learn more about each of the different research areas below.

Cancer

Bioinformatics Tool for TRANCE/TNFSF11/RANK L

Discover related pathways, diseases and genes to TRANCE/TNFSF11/RANK L. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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Related TRANCE/TNFSF11/RANK L Blog Posts

Check out the latest blog posts on TRANCE/TNFSF11/RANK L.
The diverse functions of RANKL/TRANCE/TNFSF11
RANKL (also known as TNF-related activation-induced cytokine), or receptor activator of nuclear factor-?B ligand, was first discovered as a key player in the RANKL/RANK/OPG osteoclast formation pathway. Osteoclasts are large multinucleate cells t...    Read more.
Read more TRANCE/TNFSF11/RANK L related blogs.