Rat IgG2a Isotype Control (54447) [Unconjugated]

B16-F1 mouse melanoma cell line was stained with RatAnti-Mouse Integrin beta 1/CD29 Monoclonal Antibody (Catalog # MAB2405,filled histogram) or Rat IgG Isotype Control Antibody (Catalog #MAB006,open histogram), followed by Phycoerythrin-conjugated Anti-Rat IgG SecondaryAntibody (Catalog # F0105B).

• Reactivity: Rt
• Applications: Ctrl
• Clone: 54447
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Concentration: LYOPH

Rat IgG2a Isotype Control (54447) [Unconjugated] Summary

• Immunogen: KLH
• Specificity: Selected for use as rat IgG_2A isotype control. In direct ELISAs, does not cross-react with recombinant human (rh) 6Ckine, recombinant mouse (rm) 6Ckine, rhACT II (rhMIP-1 beta ), rhBLC/BCA-1, rmBLC, rmC10, recombinant rat (rr) CINC-1, rrCINC-2 alpha , rrCINC-2 beta , rrCINC-3, rhCK beta 8-1, recombinant viral (rv) CMV UL146, rmCRG-2, rhENA-78, rhEotaxin, rmEotaxin, rhEotaxin 2, rhEotaxin-3, rmEotaxin 2, rhFractalkine, rmFractalkine, rrFractalkine, rhGCP-2, rmGCP-2, rhGRO alpha , rhGRO beta , rhGRO gamma , rhHCC-1, rhHCC-4, rhI-309, rhIL-8, recombinant porcine IL-8, rhIP-10, rhI-TAC, rmJE, rmKC, rhLeukotactin -1, rhLymphytactin, rmLymphotactin, rmMARC, rhMCP-1, rhMCP-2, rhMCP-3, rhMCP-4, rmMCP-5, rvMCV Type 2, rhMDC, rmMDC, rhMIG, rmMIG, rhMIP-1 alpha , rmMIP-1 alpha , rmMIP-1 beta , rmMIP-1 gamma , rhMIP-1δ, rmMIP-2, rhMIP-3 alpha , rrMIP-3 alpha , rhMIP-3 beta , rmMIP-3 alpha , rmMIP-3 beta , rvMIP-I, rvMIP-II, rvMIP-III, rhMPIF-1, rhNAP-2, rhParc, rhRANTES, rmRANTES, rhSDF-1 alpha , rmSDF-1 alpha , rhSDF-1 beta , rhTarc, rmTARC, rmTCA-3, rhTeck, or rmTeck.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified from hybridoma culture supernatant
• Endotoxin Note: <0.10 EU per 1 μg of the antibody by the LAL method.

Applications/Dilutions

• Dilutions:
  • Control

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Rat IgG2a Isotype Control (54447) [Unconjugated]

• IgG2A

Background

R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.

Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Isotype Controls are guaranteed for 1 year from date of receipt.

Publications for IgG2a Isotype Control (MAB006)(128)

Publications using MAB006

• D Jayawarden, S Priyamvada, T Kageyama, Z White, A Kumar, TF Griggs, A Majumder, R Akram, AN Anbazhagan, T Sano, PK Dudeja Loss of SLC26A3 Results in Colonic Mucosal Immune Dysregulation via Epithelial-Immune Cell Crosstalk Cellular and Molecular Gastroenterology and Hepatology, 2022;0(0):. 2022 [PMID: 36535508] (In Vivo, Mouse)
• SL Jeong, H Zhang, S Yamaki, C Yang, DD McKemy, MR Lieber, P Pham, MF Goodman Immunoglobulin somatic hypermutation in a defined biochemical system recapitulates affinity maturation and permits antibody optimization Nucleic Acids Research, 2022;0(0):. 2022 [PMID: 36321646] (In Vivo Control, Mouse)
• A Jarade, Z Garcia, S Marie, A Demera, I Prinz, P Bousso, JP Di Santo, N Serafini Inflammation triggers ILC3 patrolling of the intestinal barrier Nature Immunology, 2022;0(0):. 2022 [PMID: 35999393] (In Vivo, Mouse)
• V Grubiši?, V Bali, DE Fried, HK Eltzschig, SC Robson, MS Mazei-Robi, BD Gulbransen Enteric glial adenosine 2B receptor signaling mediates persistent epithelial barrier dysfunction following acute DSS colitis Mucosal Immunology, 2022;0(0):. 2022 [PMID: 35869148] (Neutralization Control, Mouse)
• WZ He, M Yang, Y Jiang, C He, YC Sun, L Liu, M Huang, YR Jiao, KX Chen, J Hou, M Huang, YL Xu, X Feng, Y Liu, Q Guo, H Peng, Y Huang, T Su, Y Xiao, Y Li, C Zeng, G Lei, XH Luo, CJ Li miR-188-3p targets skeletal endothelium coupling of angiogenesis and osteogenesis during ageing Cell Death & Disease, 2022;13(5):494. 2022 [PMID: 35610206] (IHC Control, Mouse)
• J Liu, S Zhu, L Zeng, J Li, DJ Klionsky, G Kroemer, J Jiang, D Tang, R Kang DCN released from ferroptotic cells ignites AGER-dependent immune responses Autophagy, 2021;0(0):1-14. 2021 [PMID: 34964698] (Isotype Control, Mouse)
• F Yao, Y Deng, Y Zhao, Y Mei, Y Zhang, X Liu, C Martinez, X Su, RR Rosato, H Teng, Q Hang, S Yap, D Chen, Y Wang, MM Chen, M Zhang, H Liang, D Xie, X Chen, H Zhu, JC Chang, MJ You, Y Sun, B Gan, L Ma A targetable LIFR-NF-kappaB-LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis Nature Communications, 2021;12(1):7333. 2021 [PMID: 34921145] (Isotype Control, Mouse)
• MH Mursalin, PS Coburn, FC Miller, ET Livingston, R Astley, MC Callegan C-X-C Chemokines Influence Intraocular Inflammation During Bacillus Endophthalmitis Investigative Ophthalmology & Visual Science, 2021;62(14):14. 2021 [PMID: 34784411] (Neutralization, Mouse)
• A Deczkowska, E David, P Ramadori, D Pfister, M Safran, B At The, A Giladi, DA Jaitin, O Barboy, M Cohen, I Yofe, C Gur, S Shlomi-Lou, S Henri, Y Suhail, M Qiu, S Kam, H Hermon, E Lahat, G Ben Yakov, O Cohen-Ezra, Y Davidov, M Likhter, D Goitein, S Roth, A Weber, B Malissen, A Weiner, Z Ben-Ari, M Heikenwäld, E Elinav, I Amit XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis Nature Medicine, 2021;0(0):. 2021 [PMID: 34017133] (Neutralization, Mouse)
• FY Mao, YP Lv, CJ Hao, YS Teng, YG Liu, P Cheng, SM Yang, W Chen, T Liu, QM Zou, R Xie, JY Xu, Y Zhuang Helicobacter pylori-induced Rev-erb&amp;alpha fosters gastric bacteria colonization by impairing host innate and adaptive defense Cellular and Molecular Gastroenterology and Hepatology, 2021;0(0):. 2021 [PMID: 33676046] (Neutralization, Mouse)
• S Gouard, C Maurel, S Marionneau, D Dansette, C Bailly, F Guérard, N Chouin, F Haddad, C Alliot, J Gaschet, R Eychenne, F Kraeber-Bo, M Chérel Targeted-Alpha-Therapy Combining Astatine-211 and anti-CD138 Antibody in A Preclinical Syngeneic Mouse Model of Multiple Myeloma Minimal Residual Disease Cancers, 2020;12(9):. 2020 [PMID: 32971984] (Isotype Control, Mouse)
• QF Zhang, J Li, K Jiang, R Wang, JL Ge, H Yang, SJ Liu, LT Jia, L Wang, BL Chen CDK4/6 inhibition promotes immune infiltration in ovarian cancer and synergizes with PD-1 blockade in a B cell-dependent manner Theranostics, 2020;10(23):10619-10633. 2020 [PMID: 32929370] (Control, Mouse)
• J Sellau, M Groneberg, H Fehling, T Thye, S Hoenow, C Marggraff, M Weskamm, C Hansen, S Stanelle-B, S Kuehl, J Noll, V Wolf, NG Metwally, SH Hagen, C Dorn, J Wernecke, H Ittrich, E Tannich, T Jacobs, I Bruchhaus, M Altfeld, H Lotter Androgens predispose males to monocyte-mediated immunopathology by inducing the expression of leukocyte recruitment factor CXCL1 Nat Commun, 2020;11(1):3459. 2020 [PMID: 32651360] (In Vivo, Mouse)
• T Yoshida, NA Das, AJ Carpenter, R Izadpanah, SA Kumar, S Gautam, SB Bender, U Siebenlist, B Chandrasek Minocycline reverses IL-17A/TRAF3IP2-mediated p38 MAPK/NF-kappaB/iNOS/NO-dependent cardiomyocyte contractile depression and death Cell. Signal., 2020;73(0):109690. 2020 [PMID: 32553549] (Neutralization Control, Mouse)
• A Klingler, D Regensburg, C Tenkerian, N Britzen-La, A Hartmann, M Stürzl, E Naschberge Species-, organ- and cell-type-dependent expression of SPARCL1 in human and mouse tissues PLoS ONE, 2020;15(5):e0233422. 2020 [PMID: 32437418] (Isotype Control, Mouse)
• L Li, L Ni, RF Heary, S Elkabes Astroglial TLR9 antagonism promotes chemotaxis and alternative activation of macrophages via modulation of astrocyte-derived signals: implications for spinal cord injury J Neuroinflammation, 2020;17(1):73. 2020 [PMID: 32098620] (Neutralization, Mouse)
• T Ikeda, M Nishita, K Hoshi, T Honda, Y Kakeji, Y Minami Mesenchymal stem cell-derived CXCL16 promotes progression of gastric cancer cells by STAT3-mediated expression of Ror1 Cancer Sci., 2020;111(4):1254-1265. 2020 [PMID: 32012403] (Neutralization Control, Mouse)
• S Suliman, M Murphy, M Musvosvi, A Gela, EW Meermeier, H Geldenhuys, C Hopley, A Toefy, N Bilek, A Veldsman, WA Hanekom, JL Johnson, WH Boom, G Obermoser, H Huang, M Hatherill, DM Lewinsohn, E Nemes, TJ Scriba MR1-Independent Activation of Human Mucosal-Associated Invariant T Cells by Mycobacteria J. Immunol., 2019;0(0):. 2019 [PMID: 31611259] (Neutralization, Human)
• A Zychlinsky, M Rousseau, L Lacerda Ma, T Canton, CR Consiglio, ML Albert, M Fontes, D Duffy, MA Ingersoll Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection JCI Insight, 2019;5(0):. 2019 [PMID: 31145099] (In Vivo, Mouse)
• CC Tao, KM Cheng, YL Ma, WL Hsu, YC Chen, JL Fuh, WJ Lee, CC Chao, EHY Lee Galectin-3 promotes A&amp;beta oligomerization and A&amp;beta toxicity in a mouse model of Alzheimer&#039;s disease Cell Death Differ., 2020;27(1):192-209. 2020 [PMID: 31127200] (IP, Rat)
• S An, I Raju, B Surenkhuu, JE Kwon, S Gulati, M Karaman, A Pradeep, S Sinha, C Mun, S Jain Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies Ocul Surf, 2019;0(0):. 2019 [PMID: 30965123] (Isotype Control, Human)
• S Mukai, Y Ogawa, H Saya, Y Kawakami, K Tsubota Therapeutic potential of tranilast for the treatment of chronic graft-versus-host disease in mice PLoS ONE, 2018;13(10):e0203742. 2018 [PMID: 30307955] (Isotype Control, Mouse)
• BL Hoh, K Rojas, L Lin, HZ Fazal, S Hourani, KW Nowicki, MB Schneider, K Hosaka Estrogen Deficiency Promotes Cerebral Aneurysm Rupture by Upregulation of Th17 Cells and Interleukin-17A Which Downregulates E-Cadherin J Am Heart Assoc, 2018;7(8):. 2018 [PMID: 29654199] (Neutralization, Mouse)
• X Shi, S Wei, KJ Simms, DN Cumpston, TJ Ewing, P Zhang Sonic Hedgehog Signaling Regulates Hematopoietic Stem/Progenitor Cell Activation during the Granulopoietic Response to Systemic Bacterial Infection Front Immunol, 2018;9(0):349. 2018 [PMID: 29535725] (Flow Cytometry, Mouse)
• S Mukai, Y Ogawa, Y Kawakami, Y Mashima, K Tsubota Inhibition of Vascular Adhesion Protein-1 for Treatment of Graft-Versus-Host Disease in Mice FASEB J., 2018;0(0):fj201700176R. 2018 [PMID: 29490166] (IHC-Fr, Mouse)
• CC Liang, CS Li, IC Weng, HY Chen, HH Lu, CC Huang, FT Liu Galectin-9 is Critical for Mucosal Adaptive Immunity through the TH17-IgA Axis Am. J. Pathol., 2018;0(0):. 2018 [PMID: 29458010] (Neutralization Control, Mouse)
• JP Böttcher, E Bonavita, P Chakravart, H Blees, M Cabeza-Cab, S Sammicheli, NC Rogers, E Sahai, S Zelenay, C Reis E Sou NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control Cell, 2018;172(5):1022-1037.e14. 2018 [PMID: 29429633] (Neutralization, Mouse)
• JM Gu, S Yuan, D Sim, K Abe, P Liu, M Rosenbruch, P Bringmann, K Kauser Blockade of placental growth factor reduces vaso-occlusive complications in murine models of sickle cell disease Exp. Hematol., 2018;0(0):. 2018 [PMID: 29337222] (Neutralization, Mouse)
• A Okuma, A Hanyu, S Watanabe, E Hara p16Ink4a and p21Cip1/Waf1 promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis Nat Commun, 2017;8(1):2050. 2017 [PMID: 29234059] (In Vivo, Mouse)
• I Flamme, P Ellinghaus, D Urrego, T Krüger FGF23 expression in rodents is directly induced via erythropoietin after inhibition of hypoxia inducible factor proline hydroxylase PLoS ONE, 2017;12(10):e0186979. 2017 [PMID: 29073196] (Control, Rat)
• H Matsumoto, N Matsumoto, J Shimazaki, J Nakagawa, Y Imamura, K Yamakawa, T Yamada, M Ikeda, H Hiraike, H Ogura, T Shimazu Therapeutic Effectiveness of Anti-RAGE Antibody Administration in a Rat Model of Crush Injury Sci Rep, 2017;7(1):12255. 2017 [PMID: 28947744] (IHC, Rat)
• K Watanabe, CA Gilchrist, MJ Uddin, SL Burgess, MM Abhyankar, SN Moonah, Z Noor, JR Donowitz, BN Schneider, T Arju, E Ahmed, M Kabir, M Alam, R Haque, P Pramoonjag, B Mehrad, WA Petri Microbiome-mediated neutrophil recruitment via CXCR2 and protection from amebic colitis PLoS Pathog., 2017;13(8):e1006513. 2017 [PMID: 28817707] (Neutralization, Mouse)
• Y Kannan, LJ Entwistle, VS Pelly, J Perez-Llor, AW Walker, SC Ley, MS Wilson TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus PLoS Pathog., 2017;13(7):e1006536. 2017 [PMID: 28759611] (Mouse)
• M Yang, CJ Li, X Sun, Q Guo, Y Xiao, T Su, ML Tu, H Peng, Q Lu, Q Liu, HB He, TJ Jiang, MX Lei, M Wan, X Cao, XH Luo MiR-497?195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1? activity Nat Commun, 2017;8(0):16003. 2017 [PMID: 28685750] (IHC, Mouse)
• DW Kimmel, WP Dole, DE Cliffel Elucidation of the Role of Lectin-Like oxLDL Receptor-1 in the Metabolic Responses of Macrophages to Human oxLDL J Lipids, 2017;2017(0):8479482. 2017 [PMID: 28642826] (Neutralization, Mouse)
• C Stecher, C Battin, J Leitner, M Zettl, K Grabmeier-, C Höller, GJ Zlabinger, P Steinberge PD-1 Blockade Promotes Emerging Checkpoint Inhibitors in Enhancing T Cell Responses to Allogeneic Dendritic Cells Front Immunol, 2017;8(0):572. 2017 [PMID: 28588576] (Control, Human)
• Y Shi, YF Ping, W Zhou, ZC He, C Chen, BS Bian, L Zhang, L Chen, X Lan, XC Zhang, K Zhou, Q Liu, H Long, TW Fu, XN Zhang, MF Cao, Z Huang, X Fang, X Wang, H Feng, XH Yao, SC Yu, YH Cui, X Zhang, JN Rich, S Bao, XW Bian Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth Nat Commun, 2017;8(0):15080. 2017 [PMID: 28569747] (Flow Cytometry, Human)
• B Robl, SM Botter, A Boro, D Meier, D Neri, B Fuchs Evaluation of F8-TNF-? in Models of Early and Progressive Metastatic Osteosarcoma Transl Oncol, 2017;10(3):419-430. 2017 [PMID: 28448958] (IHC, Mouse)
• Y Dombrowski, T O'Hagan, M Dittmer, R Penalva, SR Mayoral, P Bankhead, S Fleville, G Eleftheria, C Zhao, M Naughton, R Hassan, J Moffat, J Falconer, A Boyd, P Hamilton, IV Allen, A Kissenpfen, PN Moynagh, E Evergren, B Perbal, AC Williams, RJ Ingram, JR Chan, RJ Franklin, DC Fitzgerald Regulatory T cells promote myelin regeneration in the central nervous system Nat. Neurosci, 2017;0(0):. 2017 [PMID: 28288125] (Mouse)
• JA Schwartz, KL Clayton, S Mujib, H Zhang, AK Rahman, J Liu, FY Yue, E Benko, C Kovacs, MA Ostrowski Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9 J. Immunol, 2017;0(0):. 2017 [PMID: 28264968] (Neutralization, Human)
• Z Noor, K Watanabe, MM Abhyankar, SL Burgess, EL Buonomo, CA Cowardin, WA Petri Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin-25-Mediated Protection from Amebic Colitis MBio, 2017;8(1):. 2017 [PMID: 28246365] (Neutralization, Mouse)
• J Gray, K Oehrle, G Worthen, T Alenghat, J Whitsett, H Deshmukh Intestinal commensal bacteria mediate lung mucosal immunity and promote resistance of newborn mice to infection Sci Transl Med, 2017;9(376):. 2017 [PMID: 28179507] (Isotype Control, Mouse)
• A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice Nat Commun, 2016;7(0):13896. 2016 [PMID: 27982034] (Flow Cytometry, Mouse)
• Hoeke A Baarsma Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD J. Exp. Med, 2016;0(0):. 2016 [PMID: 27979969] (Control, Mouse)
• Eóin N McNamee Targeting GM-CSF in epithelial and vascular remodeling in experimental Eosinophilic Esophagitis Allergy, 2016;0(0):. 2016 [PMID: 27926989] (In Vivo, Mouse)
• Basophils promote tumor rejection via chemotaxis and infiltration of CD8+ T cells Cancer Res., 2016;0(0):. 2016 [PMID: 27879269] (Mouse)
• A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression Elife, 2016;5(0):. 2016 [PMID: 27874833] (Flow Cytometry, Mouse)
• The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin Nat. Immunol., 2016;0(0):. 2016 [PMID: 27869817] (Neutralization, Mouse)
• I-Ping Chen Dietary phosphate supplement does not rescue skeletal phenotype in a mouse model for craniometaphyseal dysplasia J Negat Results Biomed, 2016;15(1):18. 2016 [PMID: 27784318] (IHC, Mouse)
• CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima Nat Immunol, 2016;0(0):. 2016 [PMID: 27668800] (Neutralization, Mouse)
• Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway J Neuroinflammation, 2016;13(1):209. 2016 [PMID: 27576490] (Control, Mouse)
• Allostimulatory Effects of Dendritic Cells with Characteristic Features of a Regulatory Phenotype PLoS ONE, 2016;11(8):e0159986. 2016 [PMID: 27525971] (Bioassay Control, Mouse)
• Thymic Stromal Lymphopoietin Neutralization Inhibits the Immune Adjuvant Effect of Di-(2-Ethylhexyl) Phthalate in Balb/c Mouse Asthma Model PLoS ONE, 2016;11(7):e0159479. 2016 [PMID: 27467143] (Control, Mouse)
• Jennifer Quantius Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair PLoS Pathog, 2016;12(6):e1005544. 2016 [PMID: 27322618] (Flow Cytometry, Mouse)
• NKG2D-NKG2D Ligand Interaction Inhibits the Outgrowth of Naturally Arising Low-Grade B Cell Lymphoma In Vivo J Immunol, 2016;196(11):4805-13. 2016 [PMID: 27183590] (Flow Cytometry, Mouse)
• ZH Song, ZY Li, DD Li, WN Fang, HY Liu, DD Yang, CY Meng, Y Yang, JP Peng Seminal plasma induces inflammation in the uterus through the ?? T/IL-17 pathway Sci Rep, 2016;6(0):25118. 2016 [PMID: 27109934] (Neutralization, Mouse)
• A Spiegel, MW Brooks, S Houshyar, F Reinhardt, M Ardolino, E Fessler, MB Chen, JA Krall, J DeCock, IK Zervantona, A Iannello, Y Iwamoto, V Cortez-Ret, RD Kamm, MJ Pittet, DH Raulet, RA Weinberg Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells Cancer Discov, 2016;0(0):. 2016 [PMID: 27072748] (In Vivo, Mouse)
• D Schlam, J Canton, M Carreño, H Kopinski, SA Freeman, S Grinstein, GD Fairn Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis MBio, 2016;7(2):. 2016 [PMID: 27048806] (Flow Cytometry, Mouse)
• Porcherie A, Gilbert F, Germon P, Cunha P, Trotereau A, Rossignol C, Winter N, Berthon P, Rainard P IL-17A Is an Important Effector of the Immune Response of the Mammary Gland to Escherichia coli Infection. J Immunol, 2016;196(2):803-12. 2016 [PMID: 26685206] (Neutralization Control, Mouse)
• Liu Y, Li K, Yang L, Tang S, Wang X, Cao G, Li S, Lei H, Zhang X Dendritic Cells Regulate Treg-Th17 Axis in Obstructive Phase of Bile Duct Injury in Murine Biliary Atresia. PLoS ONE, 2015;10(9):e0136214. 2015 [PMID: 26325187] (Neutralization Control, Mouse)
• Barreira da Silva R, Laird M, Yatim N, Fiette L, Ingersoll M, Albert M Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy. Nat Immunol, 2015;16(8):850-8. 2015 [PMID: 26075911] (Neutralization, Mouse)
• Abdel Fattah E, Bhattacharya A, Herron A, Safdar Z, Eissa N Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency. J Immunol, 2015;194(11):5407-16. 2015 [PMID: 25888640] (Neutralization Control, Mouse)
• Sottnik J, Dai J, Zhang H, Campbell B, Keller E Tumor-induced pressure in the bone microenvironment causes osteocytes to promote the growth of prostate cancer bone metastases. Cancer Res, 2015;75(11):2151-8. 2015 [PMID: 25855383] (Neutralization Control, Human)
• Negishi-Koga T, Gober H, Sumiya E, Komatsu N, Okamoto K, Sawa S, Suematsu A, Suda T, Sato K, Takai T, Takayanagi H Immune complexes regulate bone metabolism through FcRgamma signalling. Nat Commun, 2015;6(0):6637. 2015 [PMID: 25824719] (Flow Cytometry, Mouse)
• Yang B, Liu R, Yang T, Jiang X, Zhang L, Wang L, Wang Q, Luo Z, Liu E, Fu Z Neonatal Streptococcus pneumoniae infection may aggravate adulthood allergic airways disease in association with IL-17A. PLoS ONE, 2015;10(3):e0123010. 2015 [PMID: 25816135] (Neutralization Control, Mouse)
• Arulmoli J, Pathak M, McDonnell L, Nourse J, Tombola F, Earthman J, Flanagan L Static stretch affects neural stem cell differentiation in an extracellular matrix-dependent manner. Sci Rep, 2015;5(0):8499. 2015 [PMID: 25686615]
• Wang X, Bi Y, Xue L, Liao J, Chen X, Lu Y, Zhang Z, Wang J, Liu H, Yang H, Liu G The calcineurin-NFAT axis controls allograft immunity in myeloid-derived suppressor cells through reprogramming T cell differentiation. Mol Cell Biol, 2015;35(3):598-609. 2015 [PMID: 25452304] (Neutralization, Mouse)
• Kowalewska P, Patrick A, Fox-Robichaud A Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation. PLoS ONE, 2014;9(9):e104537. 2014 [PMID: 25184228] (IHC-Fr, Mouse)
• Liu , Jinlin, Ke , Fang, Xu , Zhenyao, Liu , Zhaoyuan, Zhang , Lingyun, Yan , Sha, Wang , Zhe, Wang , Hong, Wang , Honglin CCR6 is a prognostic marker for overall survival in patients with colorectal cancer, and its overexpression enhances metastasis in vivo. PLoS ONE, 2014;9(6):e101137. 2014 [PMID: 24979261] (Neutralization, Mouse)
• Dulek D, Newcomb D, Goleniewska K, Cephus J, Zhou W, Reiss S, Toki S, Ye F, Zaynagetdinov R, Sherrill T, Blackwell T, Moore M, Boyd K, Kolls J, Peebles R Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner. Infect Immun, 2014;82(9):3723-39. 2014 [PMID: 24958709] (Neutralization, Mouse)
• Giordano D, Draves K, Li C, Hohl T, Clark E Nitric oxide regulates BAFF expression and T cell-independent antibody responses. J Immunol, 2014;193(3):1110-20. 2014 [PMID: 24951820] (Flow Cytometry, Mouse)
• Mathews J, Williams A, Brand J, Wurmbrand A, Chen L, Ninin F, Si H, Kasahara D, Shore S gammadelta T cells are required for pulmonary IL-17A expression after ozone exposure in mice: role of TNFalpha. PLoS ONE, 2014;9(5):e97707. 2014 [PMID: 24823369] (Neutralization, Mouse)
• Morshed M, Hlushchuk R, Simon D, Walls A, Obata-Ninomiya K, Karasuyama H, Djonov V, Eggel A, Kaufmann T, Simon H, Yousefi S NADPH oxidase-independent formation of extracellular DNA traps by basophils. J Immunol, 2014;192(11):5314-23. 2014 [PMID: 24771850] (Isotype Control, Mouse)
• Chu V, Beller A, Rausch S, Strandmark J, Zanker M, Arbach O, Kruglov A, Berek C Eosinophils promote generation and maintenance of immunoglobulin-A-expressing plasma cells and contribute to gut immune homeostasis. Immunity, 2014;40(4):582-93. 2014 [PMID: 24745334] (Neutralization, Mouse)
• Tseng J, Yang C, Liang S, Liu R, Yang S, Lin J, Chen Y, Wu Y, Jiang J, Lin C Interleukin-17A modulates circulating tumor cells in tumor draining vein of colorectal cancers and affects metastases. Clin Cancer Res, 2014;20(11):2885-97. 2014 [PMID: 24677375] (Neutralization, Mouse)
• Gerlini A, Colomba L, Furi L, Braccini T, Manso A, Pammolli A, Wang B, Vivi A, Tassini M, Van Rooijen N, Pozzi G, Ricci S, Andrew P, Koedel U, Moxon E, Oggioni M The role of host and microbial factors in the pathogenesis of pneumococcal bacteraemia arising from a single bacterial cell bottleneck. PLoS Pathog, 2014;10(3):e1004026. 2014 [PMID: 24651834] (Flow Cytometry, Mouse)
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Review for IgG2a Isotype Control (MAB006) (1)

Average Rating: 5

(Based on 1 review)

reviewed by: A G 06/13/2017

Summary

• Lot: CA02315081