TRAM/TICAM2 Antibody

Images

 
Western Blot: TRAM/TICAM2 Antibody [NBP1-77199] - Human (A), mouse (B), and rat (C) kidney cell lysates with TICAM2 antibody (C2) at 1 ug/ml.
Immunohistochemistry-Paraffin: TRAM/TICAM2 Antibody [NBP1-77199] - Mouse kidney using TICAM2 antibody at 2 ug/ml.
Immunofluorescence: TRAM/TICAM2 Antibody [NBP1-77199] - Immunofluorescence of TIRP in Mouse Kidney cells with TIRP antibody at 20 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

TRAM/TICAM2 Antibody Summary

Immunogen
Antibody was raised against a peptide corresponding to amino acids near the C-terminus of human TIRP. The immunogen is located within the last 50 amino acids of TIRP.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TICAM2
Purity
Ion exchange chromatography
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/ml
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/ml
  • Immunohistochemistry 2 ug/ml
  • Immunohistochemistry-Paraffin 2 ug/mL
Application Notes
TIRP antibody can be used for detection of TIRP by Western blot at 0.5 to 2 mg/ml.
Control Peptide
TRAM/TICAM2 Peptide (NBP1-77199PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Ion exchange chromatography

Alternate Names for TRAM/TICAM2 Antibody

  • MGC129876
  • MGC129877
  • Putative NF-kappa-B-activating protein 502
  • TICAM2
  • TICAM-2TIR domain-containing adapter molecule 2
  • TIRAP3
  • TIRP
  • TIRPcytoplasmic adaptor
  • toll/interleukin-1 receptor (TIR) domain-containing adapter protein
  • Toll/interleukin-1 receptor domain-containing protein
  • toll-like receptor adaptor molecule 2
  • Toll-like receptor adaptor protein 3
  • TRAM
  • TRAMNF-kappa-B-activating protein 502
  • Trif
  • TRIF-related adapter molecule
  • TRIF-related adaptor molecule

Background

TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kappaB. Expression of TIRP appears to be essential for TLR4 signalling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TICAM2
Entrez
Uniprot