TRAM/TICAM2 Products

Antibodies
TRAM/TICAM2 Antibody
TRAM/TICAM2 Antibody
Species: Hu, Mu, Rt
Applications: WB, CyTOF-ready, Flow, ICC/IF
Host: Goat Polyclonal
Formulation Catalog # Availability Price  
TRAM/TICAM2 Antibody
TRAM/TICAM2 Antibody
NBP2-24686
Species: Hu, Mu, Rt, Bv, Op, Pm
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
TRAM/TICAM2 Antibody
TRAM/TICAM2 Antibody
NBP2-24638
Species: Hu, Pm
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
TRAM/TICAM2 Overexpression Ly ...
TRAM/TICAM2 Overexpression Lysate
NBL1-16908
Species: Hu
Applications: WB
Proteins
Recombinant Human TRAM/TICAM2 ...
Recombinant Human TRAM/TICAM2 Protein
NBP1-78901
Species: Hu
Applications: PAGE
TRAM/TICAM2 Blocking Peptide
TRAM/TICAM2 Blocking Peptide
NBP1-76616PEP
Species: Hu
Applications: AC
TRAM/TICAM2 Blocking Peptide
TRAM/TICAM2 Blocking Peptide
NBP1-77199PEP
Species: Hu
Applications: AC

Description

TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kappaB (5). Expression of TIRP appears to be essential for TLR4 signalling (6).

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 353376
Alternate Names
  • MGC129877
  • TRIF-related adapter molecule
  • MGC129876
  • Toll/interleukin-1 receptor domain-containing protein
  • TIRAP3
  • TRIF-related adaptor molecule
  • Toll-like receptor adaptor protein 3
  • toll/interleukin-1 receptor (TIR) domain-containing adapter protein
  • Putative NF-kappa-B-activating protein 502
  • TICAM-2TIR domain-containing adapter molecule 2
  • TRAMNF-kappa-B-activating protein 502
  • TIRPcytoplasmic adaptor
  • toll-like receptor adaptor molecule 2

PTMs for TRAM/TICAM2

Learn more about PTMs related to TRAM/TICAM2.

Phosphorylation
Cleavage
Myristoylation

Bioinformatics Tool for TRAM/TICAM2

Discover related pathways, diseases and genes to TRAM/TICAM2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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