Use in FLOW reported in scientific literature (PMID: 12795746). Use in Flow-cell surface reported in scientific literature (PMID: 12173037).
36 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
Peptide affinity purified
Alternate Names for TRAILR4/TNFRSF10D/DcR2 Antibody - BSA Free
DCR2decoy with truncated death domain
Decoy receptor 2
TNF receptor-related receptor for TRAIL
TNF-related apoptosis-inducing ligand receptor 4
TRAILR4TRAIL receptor 4
TRUNDDTRAIL receptor with a truncated death domain
tumor necrosis factor receptor superfamily member 10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncateddeath domain
Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD. DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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