TRAILR4/TNFRSF10D/DcR2 Products

Description

TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation, but differs in its inability to induce apoptosis. Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors.

Bioinformatics

Entrez	8793 Human
Uniprot	Q9UBN6 Human NM_003840 Human NP_003831 Human
Product By Gene ID	8793
Alternate Names	TRAIL-R4 CD264 antigen Decoy receptor 2 tumor necrosis factor receptor superfamily member 10D DcR2 TNF receptor-related receptor for TRAIL CD264 DCR2decoy with truncated death domain TRUNDDTRAIL receptor with a truncated death domain TRAILR4TRAIL receptor 4 TNF-related apoptosis-inducing ligand receptor 4 tumor necrosis factor receptor superfamily, member 10d, decoy with truncateddeath domain

Diseases related to TRAILR4/TNFRSF10D/DcR2

Discover more about diseases related to TRAILR4/TNFRSF10D/DcR2.

Malignant Neoplasms
Neoplasms
Carcinoma
Neuroblastoma
Prostatic Neoplasms
Malignant Neoplasm Of Prostate
Adenocarcinoma
Malignant Paraganglionic Neoplasm
Malignant Tumor Of Colon
Malignant Neoplasm Of Breast
Mammary Neoplasms
Inflammation
Carcinogenesis
Lymphoma
Ovarian Neoplasm
Malignant Neoplasm Of Ovary
Colorectal Cancer
Colonic Neoplasms
Cell Transformation, Neoplastic

Pathways for TRAILR4/TNFRSF10D/DcR2

View related products by pathway and learn more about each of the pathways below.

Methylation
Cell Death
Pathogenesis
Dna Methylation
Sensitization
Cell Proliferation
Programmed Cell Death
Cellular Senescence
Senescence
Gene Silencing
Dna Hypomethylation
Aging
Response To Virus
Regulation Of Programmed Cell Death
Cell Cycle Arrest
Inflammatory Response
Cell Cycle
Cell Differentiation
Hypermethylation Of Cpg Island
Cell Killing

Research Areas for TRAILR4/TNFRSF10D/DcR2

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Cell Biology
Cytokine Research
Immunology
Innate Immunity

PTMs for TRAILR4/TNFRSF10D/DcR2

Learn more about PTMs related to TRAILR4/TNFRSF10D/DcR2.

Methylation
Cleavage
Phosphorylation
Demethylation

Bioinformatics Tool for TRAILR4/TNFRSF10D/DcR2

Discover related pathways, diseases and genes to TRAILR4/TNFRSF10D/DcR2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.