TRAILR4/TNFRSF10D/DcR2 Products

Description

TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation, but differs in its inability to induce apoptosis. Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors.

Bioinformatics

Entrez	8793 Human
Uniprot	NM_003840 Human NP_003831 Human Q9UBN6 Human
Product By Gene ID	8793
Alternate Names	CD264 antigen CD264 DcR2 DCR2decoy with truncated death domain Decoy receptor 2 TNF receptor-related receptor for TRAIL TNF-related apoptosis-inducing ligand receptor 4 TRAIL-R4 TRAILR4TRAIL receptor 4 TRUNDDTRAIL receptor with a truncated death domain tumor necrosis factor receptor superfamily member 10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncateddeath domain

Research Areas for TRAILR4/TNFRSF10D/DcR2

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Cell Biology
Cytokine Research
Immunology
Innate Immunity