Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IP, KD
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, KD
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
TPR encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
7175 |
Alternate Names |
- nuclear pore complex-associated protein TPR
- nucleoprotein TPR
- translocated promoter region (to activated MET oncogene)
- tumor potentiating region
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