Recombinant Human TNF RI/TNFRSF1A Protein

Product Discontinued

Recombinant Human TNF RI/TNFRSF1A Protein Summary

• Description: Recombinant bioactive protein containing 162 amino acids for Human TNF RI/TNFRSF1A
  
  

  Source:E. coli
  Amino Acid Sequence:(AAA36756)

• Preparation Method: Determined to be >98% pure by SDS-PAGE
• Details of Functionality: The biological activity of sTNF-RI was determined by its inhibitory effect of the TNF-a mediated cytotoxicity in murine L-929 cells. The ED50 for the effect in the presence of 0.25 ng/ml of recombinant TNF-a, is 0.05 mg/ml.
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: TNFRSF1A
• Purity: >98%, by SDS-PAGE
• Endotoxin Note: <0.1 ng/ug

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Theoretical MW: 18.3 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C.
• Buffer: Sterile filtered and lyophilized from 5 mM Tris (pH 8.0).
• Concentration: Lyoph
• Purity: >98%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute in 5 mM Tris, pH 8.0 to a concentration of 1 mg/ml. This solution can then be diluted into other aqueous buffers.

Alternate Names for Recombinant Human TNF RI/TNFRSF1A Protein

• CD120a antigen
• CD120a
• FPF
• p55
• p55-R
• p60
• TNF RI
• TNFARMGC19588
• TNF-R
• TNF-R1
• TNFR1TBP1
• TNFR55
• TNF-R55
• TNFR60
• TNFRI
• TNF-RI
• TNF-R-I
• TNFR-I
• TNFRSF1A
• tumor necrosis factor binding protein 1
• Tumor necrosis factor receptor 1
• tumor necrosis factor receptor 1A isoform beta
• tumor necrosis factor receptor superfamily member 1A
• tumor necrosis factor receptor superfamily, member 1A
• tumor necrosis factor receptor type 1
• Tumor necrosis factor receptor type I
• tumor necrosis factor-alpha receptor

Background

Tumor Necrosis Factor receptor type I (TNF-RI) is also referred as p60. The p60 form of the receptor is primarily expressed on epithelial cells. Recombinant Human soluble TNF receptor Type I (sTNF-RI) is a 18.3 kDa protein containing 162 amino acid residues comprising the extra Cellular domain of TNF Receptor Type I.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: TNFRSF1A