TNF RI/TNFRSF1A Antibody (16805)

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Recombinant Human TNF RI/TNFRSF1A (Catalog # 636‑R1) inhibits Recombinant Human TNF‑ alpha (Catalog # 210‑TA) induced cytotoxicity in the L‑929 mouse fibroblast cell line in a dose-dependent manner (orange ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, B/N, ELISA(Cap)
Clone
16805
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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Catalog# & Formulation Size Price

TNF RI/TNFRSF1A Antibody (16805) Summary

Immunogen
E. coli-derived recombinant human TNF RI/TNFRSF1A
Extracellular domain
Specificity
Detects human TNF RI/TNFRSF1A in ELISAs and Western blots. In sandwich immunoassays, no significant cross-reactivity or interference with recombinant human (rh) TGF-alpha, hTGF-beta 1, porcine (p) TGF-beta 1, rhTGF-beta 1, pTGF-beta 1.2, pTGF-beta 2, recombinant chicken TGF-beta 3, rhTGF-beta 3, recombinant amphibian TGF-beta 5, rhTNF-beta, or rhTNF RII is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF1A
Purity
Protein A or G purified from ascites
Endotoxin Note
<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
  • ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL
  • Neutralization 1-6 ug/mL
  • ELISA Standard (Matched Pair)
Application Notes
ELISA Detection: Human TNF RI/TNFRSF1A Biotinylated Antibody (Catalog number BAF225)
Standard: Recombinant Human TNF RI/TNFRSF1A (Catalog number 636-R1)
Publications
Read Publications using
MAB625 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Purity
Protein A or G purified from ascites
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TNF RI/TNFRSF1A Antibody (16805)

  • CD120a antigen
  • CD120a
  • FPF
  • p55
  • p55-R
  • p60
  • TNF RI
  • TNFARMGC19588
  • TNF-R
  • TNF-R1
  • TNFR1TBP1
  • TNFR55
  • TNF-R55
  • TNFR60
  • TNFRI
  • TNF-RI
  • TNF-R-I
  • TNFR-I
  • TNFRSF1A
  • tumor necrosis factor binding protein 1
  • Tumor necrosis factor receptor 1
  • tumor necrosis factor receptor 1A isoform beta
  • tumor necrosis factor receptor superfamily member 1A
  • tumor necrosis factor receptor superfamily, member 1A
  • tumor necrosis factor receptor type 1
  • Tumor necrosis factor receptor type I
  • tumor necrosis factor-alpha receptor

Background

TNF RI occurs both in membrane bound and soluble forms and functions as a receptor for TNF-alpha and TNF-beta. In the superfamily nomenclature, it is designated TNFRSF1A.

 

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TNF RI/TNFRSF1A Antibody (MAB625)(18)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 9 applications: Antibody Array Development, Array Development, ELISA Development, ELISA Development (Capture), Flow Cytometry, Functional Assay, Neutralization, Neutralizing, Western Blot.


Filter By Application
Antibody Array Development
(1)
Array Development
(1)
ELISA Development
(5)
ELISA Development (Capture)
(1)
Flow Cytometry
(2)
Functional Assay
(1)
Neutralization
(4)
Neutralizing
(1)
Western Blot
(1)
All Applications
Filter By Species
Human
(18)
All Species
Showing Publications 1 - 10 of 18. Show All 18 Publications.
Publications using MAB625 Applications Species
L Bin, X Li, B Richers, JE Streib, JW Hu, P Taylor, DYM Leung ANKRD1 regulates innate immune responses against herpes simplex virus 1: A potential role in eczema herpeticum J. Allergy Clin. Immunol., 2018;0(0):. 2018 [PMID: 29371118] (Neutralizing, Human) Neutralizing Human
CD16 is indispensable for antibody-dependent cellular cytotoxicity by human monocytes Sci Rep, 2016;6(0):34310. 2016 [PMID: 27670158] (Human) Human
Steeland S, Puimege L, Vandenbroucke R, Van Hauwermeiren F, Haustraete J, Devoogdt N, Hulpiau P, Leroux-Roels G, Laukens D, Meuleman P, De Vos M, Libert C Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1. J Biol Chem, 2015;290(7):4022-37. 2015 [PMID: 25538244] (ELISA Development (Capture), Human) ELISA Development (Capture) Human
Denoyer A, Godefroy D, Celerier I, Frugier J, Riancho L, Baudouin F, Rostene W, Baudouin C CX3CL1 expression in the conjunctiva is involved in immune cell trafficking during toxic ocular surface inflammation. Mucosal Immunol, 2012;5(0):702. 2012 [PMID: 22692452] (Neutralization, Human) Neutralization Human
Zhao X, Qureshi F, Eastman PS, Manning WC, Alexander C, Robinson WH, Hesterberg LK Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritis. J. Immunol. Methods, 2012;378(1):72-80. 2012 [PMID: 22366959] (ELISA Development, Human) ELISA Development Human
Krausgruber T, Saliba D, Ryzhakov G IRF5 is required for late-phase TNF secretion by human dendritic cells. Blood, 2010;115(22):4421-30. 2010 [PMID: 20237317] (Neutralization, Human) Neutralization Human
Hu H, Kwun J, Aizenstein BD, Knechtle SJ Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. Transplantation, 2009;87(12):1814-20. 2009 [PMID: 19543058] (Antibody Array Development, Human) Antibody Array Development Human
Emsley HC, Smith CJ, Gavin CM Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production. BMC Neurol, 2007;7(0):5. 2007 [PMID: 17328808] (ELISA Development, Human) ELISA Development Human
Lee SY, Cherla RP, Tesh VL Simultaneous induction of apoptotic and survival signaling pathways in macrophage-like THP-1 cells by Shiga toxin 1. Infect. Immun., 2007;75(3):1291-302. 2007 [PMID: 17194804] (Functional Assay, Human) Functional Assay Human
Edwards JR, Sun SG, Locklin R, Shipman CM, Adamopoulos IE, Athanasou NA, Sabokbar A LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis. Arthritis Rheum., 2006;54(5):1451-62. 2006 [PMID: 16649193] (Neutralization, Human) Neutralization Human
Show All 18 Publications.

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Bioinformatics

Gene Symbol TNFRSF1A