TMEM97 Antibody

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Western Blot: TMEM97 Antibody [NBP1-30437] - Western blot analysis of TMEM97 in NIH/3T3 using NBP1-30437.

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB, ICC/IF (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.1 mg/ml

TMEM97 Antibody Summary

Immunogen
Synthetic peptide made to an internal portion of the mouse TMEM97 protein (within residues 20-100. [Swiss-Prot# Q8VD00]
Localization
Membrane; Multi-pass membrane protein
Predicted Species
Rat (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TMEM97
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 2 ug/ml
Application Notes
This TMEM97 antibody is useful for Western blot where a band is seen ~24 kDa. It is not recommended for ICC/IF. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
TMEM97 Peptide (NBP1-30437PEP)

Reactivity Notes

Mouse. Immunogen sequence has 93% homology with rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS and 30% Glycerol
Preservative
0.1% Sodium Azide
Concentration
1.1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TMEM97 Antibody

  • MAC30Protein MAC30
  • transmembrane protein 97

Background

TMEM97 (transmembrane protein 97 or protein MAC30) is a member of IGFBP/insulin-like growth factor-binding protein family and is implicated in several biological processes wherein it acts through its regulatory effects on IGF activity. It is a multi-pass membrane protein which is localized in nuclear and cell membranes, RER and lysosomes, and is expressed in several normal tissues including brain, lung, heart, skeletal muscles, testis, ovary, and pregnant uterus. TMEM97 was originally identified as overexpressed in meningiomas, however, later it was found to exhibit altered expression in different types of cancers. The absence or downregulation of TMEM97 expression in pancreatic cancer suggests that it may acts as a tumor suppressor in pancreatic cancer. Contrastingly, its expression is stronger in breast, esophageal, stomach, colon, and oral squamous cell cancers than the corresponding normal tissues. Its physiological function is largely unknown, however, it has been suggested to implicate in cellular proliferation/differentiation and regulation of cholesterol homeostasis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for TMEM97 Antibody (NBP1-30437) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-30437AF405
Alexa Fluor 488 Labeled NBP1-30437AF488
Alexa Fluor 647 Labeled NBP1-30437AF647
Alexa Fluor 700 Labeled NBP1-30437AF700
Biotin Labeled NBP1-30437B
DyLight 405 Labeled NBP1-30437V
DyLight 488 Labeled NBP1-30437G
DyLight 550 Labeled NBP1-30437R
DyLight 650 Labeled NBP1-30437C
FITC Labeled NBP1-30437F
HRP Labeled NBP1-30437H

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Diseases for TMEM97 Antibody (NBP1-30437)

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Blogs on TMEM97.

First Commercial TMEM97 Antibody Launched
We at Novus Biologicals recently created excitement when we added TMEM97 antibody to our database. We are the first antibody suppliers to offer a product targeted to TMEM97.TMEM97 (transmembrane protein 97, also known as MAC30) is a multi-cross tran...  Read full blog post.

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Bioinformatics

Gene Symbol TMEM97
Entrez
Uniprot