TMEM70 Antibody - BSA Free

Western Blot: TMEM70 Antibody [NBP1-77131] - Human liver tissue lysate 1 ug/mL.

Immunohistochemistry-Paraffin: TMEM70 Antibody [NBP1-77131] - Rat liver tissue with TMEM70 antibody at 5 ug/mL.

Immunocytochemistry/ Immunofluorescence: TMEM70 Antibody - BSA Free [NBP1-77131] - Immunofluorescence of TMEM70 in rat liver tissue with TMEM70 antibody at 20 ug/mL.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

TMEM70 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit TMEM70 Antibody - BSA Free (NBP1-77131) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 14 amino acid synthetic peptide near the center of human TMEM70. The immunogen is located within amino acids 150 - 200 of TMEM70. Amino Acid Squence: RLYHEATTDTYKAI
• Predicted Species: Bovine (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TMEM70
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1 ug/ml
• Control Peptide:

  TMEM70 Peptide (NBP1-77131PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for TMEM70 Antibody - BSA Free

• FLJ20533
• transmembrane protein 70
• transmembrane protein 70, mitochondrial

Background

TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TMEM70
• Uniprot:
  • NP_060336(Human)