TMEM70 Antibody

Images

 
Western Blot: TMEM70 Antibody [NBP1-77131] - Human liver tissue lysate 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: TMEM70 Antibody [NBP1-77131] - Immunofluorescence of TMEM70 in rat liver tissue with TMEM70 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: TMEM70 Antibody [NBP1-77131] - Rat liver tissue with TMEM70 antibody at 5 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P, IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

TMEM70 Antibody Summary

Immunogen
Antibody was raised against a 14 amino acid synthetic peptide near the center of human TMEM70. The immunogen is located within amino acids 150 - 200 of TMEM70.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TMEM70
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1 ug/ml
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunofluorescence
Control Peptide
TMEM70 Peptide (NBP1-77131PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TMEM70 Antibody

  • FLJ20533
  • transmembrane protein 70
  • transmembrane protein 70, mitochondrial

Background

TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TMEM70
Uniprot