Western Blot: WWP1 Antibody (1A7) [H00011059-M01] - Analysis of WWP1 expression in transfected 293T cell line by WWP1 monoclonal antibody (M01A), clone 1A7.Lane 1: WWP1 transfected lysate(105.2 KDa).Lane 2: ...read more
Immunocytochemistry/ Immunofluorescence: WWP1 Antibody (1A7) [H00011059-M01] - Analysis of monoclonal antibody to WWP1 on A-431 cell. Antibody concentration 10 ug/ml.
Immunohistochemistry-Paraffin: WWP1 Antibody (1A7) [H00011059-M01] - Analysis of monoclonal antibody to WWP1 on formalin-fixed paraffin-embedded human stomach. Antibody concentration 3 ug/ml.
Western Blot: WWP1 Antibody (1A7) [H00011059-M01] - WWP1 expression in A-431 ( Cat # L015V1 ).
Immunoprecipitation: WWP1 Antibody (1A7) [H00011059-M01] - Analysis of WWP1 transfected lysate using anti-WWP1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with WWP1 MaxPab rabbit polyclonal ...read more
ELISA: WWP1 Antibody (1A7) [H00011059-M01] - Detection limit for recombinant GST tagged WWP1 is 0.03 ng/ml as a capture antibody.
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for WWP1 Antibody (1A7)
AIP5Nedd-4-like ubiquitin-protein ligase
atrophin-1 interacting protein 5
Atrophin-1-interacting protein 5
NEDD4-like E3 ubiquitin-protein ligase WWP1
TGIF-interacting ubiquitin ligase 1
WW domain containing E3 ubiquitin protein ligase 1
WW domain-containing protein 1
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Ross J S, Slodkowska E, Sheehan C E et al. Ww Domain Containing E3 Ubiquitin Protein Ligase 1 (Wwp1) Expression in Breast Cancer Its Correlation with Estrogen Receptor (Er) Insulin-like Growth Factor Receptor 1 (Igf-1r) Status. 44th Annual Meeting of the American Society of Clinical Oncology (ASCO); Chicago, IL; USA. May 30, 2008.
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