TM2D1 Antibody - BSA Free

Western Blot: TM2D1 Antibody [NBP2-94311] - Analysis of extracts of various cell lines, using TM2D1 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 90s.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

TM2D1 Antibody - BSA Free Summary

• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 38-207 of human TM2D1 (NP_114416.1). TSAGGEESLKCEDLKVGQYICKDPKINDATQEPVNCTNYTAHVSCFPAPNITCKDSSGNETHFTGNEVGFFKPISCRNVNGYSYKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFILISMQIVGPSDGSSYIIDYYGTRLTRLSITNETFRKTQLYP
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TM2D1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:2000
• Theoretical MW: 22 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for TM2D1 Antibody - BSA Free

• BBPBeta-amyloid-binding protein
• hBBP
• TM2 domain containing 1
• TM2 domain-containing protein 1

Background

The protein encoded by the TM2D1 gene is a beta-amyloid peptide-binding protein. It contains a structural module related tothat of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important inheterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neurondeath and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be atarget of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicitythrough a G protein-regulated program of cell death. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TM2D1