TLE2 Antibody [HRP]

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: HRP

TLE2 Antibody [HRP] Summary

• Immunogen: E. coli-derived recombinant human TLE2
  Ile11-Ser193
  Accession # Q04725
• Specificity: Detects human TLE2 in direct ELISAs. In direct ELISAs, less than 2% cross-reactivity with recombinant human (rh) TLE1, rhTLE3, and rhTLE4 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: TLE2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Antigen Affinity-purified

Alternate Names for TLE2 Antibody [HRP]

• enhancer of split groucho 2
• ESG
• ESG2
• ESG2Enhancer of split groucho-like protein 2
• FLJ41188
• GRG2
• TLE2
• transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
• transducin-like enhancer of split 2, homolog of Drosophila E(sp1)
• transducin-like enhancer protein 2

Background

Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TLE2