Western Blot: CDT2 Antibody [NB100-40840] - Detection of Human DTL/CDT2 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; ...read more
Immunohistochemistry-Paraffin: CDT2 Antibody [NB100-40840] - Human colon carcinoma (left) and mouse hybridoma tumor (right). Antibody used at a dilution of 1:1,000.
Immunohistochemistry-Paraffin: CDT2 Antibody [NB100-40840] - FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-DTL/CDT2 used at a dilution of 1:250. Detection: DAB staining using ...read more
The immunogen recognized by this antibody maps to a region between residue 680 and the C-terminus (residue 730) of human Denticleless Homolog (Chromatin Licensing and DNA Replicating Factor 2) using the numbering given in entry NP_057532.1 (GeneID 51514)
Monkey (100%), Primate (100%)
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Crab-eating macaque and Northern white-cheeked gibbon.
Alternate Names for CDT2 Antibody
CDT2RA-regulated nuclear matrix-associated protein
DCAF2DDB1 and CUL4 associated factor 2
DDB1- and CUL4-associated factor 2
denticleless homolog (Drosophila)
L2DTLRA regulated nuclear matrix associated protein
Lethal(2) denticleless protein homolog
RAMPdenticleless protein homolog
Retinoic acid-regulated nuclear matrix-associated protein
DTL promotes genomic stability through two distinct mechanisms. First, it is an essential component of the CUL4-DDB1 complex that controls CDT1 levels, thereby preventing rereplication. Second, it is required for the early G2/M checkpoint.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.