Thrombopoietin/THPO Antibody (378120) [DyLight 594]

• Reactivity: Mu
• Applications: WB, ELISA, ELISA(Cap), ELISA(Det)
• Clone: 378120
• Clonality: Monoclonal
• Host: Rat
• Conjugate: DyLight 594

Thrombopoietin/THPO Antibody (378120) [DyLight 594] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Thrombopoietin/Tpo
  Ser22-Thr356 (predicted)
  Accession # P40226
• Specificity: Detects mouse Thrombopoietin/Tpo in ELISAs and Western blots. In sandwich immunoassays, 0.65% cross-reactivity with NS0-derived recombinant human (rh) Tpo is observed. No significant cross-reactivity or interference with rhEPO, recombinant mouse (rm) G-CSF, rmGM-CSF, rmM-CSF, rmSCF, rmTpo R, or rmVEGF is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: THPO
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Thrombopoietin/THPO Antibody (378120) [DyLight 594]

• Megakaryocyte colony-stimulating factor
• Megakaryocyte growth and development factor
• megakaryocyte stimulating factor
• MGDF
• MGDFC-mpl ligand
• MKCSF
• MK-CSF
• ML
• MPL ligand
• MPLLG
• MPLLGMGC163194
• Myeloproliferative leukemia virus oncogene ligand
• THCYT1
• THPO
• thrombopoietin nirs variant 1
• Thrombopoietin
• Tpo
• TPOMKCSF

Background

Thrombopoietin is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/cMPL, the product of myeloproliferative leukemia virus oncogene. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: THPO