THRAP3 Antibody - BSA Free

Western Blot: THRAP3 Antibody [NBP2-24477] - Analysis of human Thyroid hormone receptor associated protein 3 in HeLa cell lysate in the 1) absence and 2) presence of immunizing peptide using NBP2-24477 at 0.1 ug/ml.

Immunohistochemistry-Paraffin: THRAP3 Antibody [NBP2-24477] - IHC analysis of human colon using NBP2-24477 at 10 ug/ml.

• Reactivity: Hu, Pm, Mu, Bv, Ca, Ch, Pm, Eq, Pm
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

THRAP3 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit THRAP3 Antibody - BSA Free (NBP2-24477) is a polyclonal antibody validated for use in IHC and WB. Anti-THRAP3 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A portion of amino acids 930-955 of human Thyroid hormone receptor associated protein 3 was used as the immunogen
• Predicted Species: Mouse (100%), Chimpanzee (100%), Bovine (100%), Monkey (100%), Equine (100%), Canine (100%), Chicken (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: THRAP3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Western Blot 0.1-1 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for THRAP3 Antibody - BSA Free

• FLJ22082
• MGC133082
• MGC133083
• thyroid hormone receptor associated protein 3
• Thyroid hormone receptor-associated protein complex 150 kDa component
• thyroid hormone receptor-associated protein, 150 kDa subunit
• Trap150
• TRAP150thyroid hormone receptor-associated protein 3

Background

Thyroid hormone receptors (TRs) are ligand dependent members of the steroid/retinoic acid superfamily of transcription factors. The two genes encoding TRs identified to date, TR alpha and TR beta, have been mapped to human chromosomes 17 and 3, respectively. TRs bind to thyroid hormone response elements (TREs) with half site binding motifs in the orientation of palindromes, direct repeats, or inverted palindromes. The affinities of binding are both variable and influenced differentially by 3,5,3 triiodo L thyronine (T3). Thyroid hormones, through their interaction with the thyroid receptor (TR), effect metabolic processes, growth and development in many tissues by regulating the expression of genes for growth hormone, malic enzyme and several hepatic proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for THRAP3 Antibody (NBP2-24477)(1)

Publication using NBP2-24477

• Zhou, L;Li, H;Sun, S;Zhang, T;Yu, Y;Xu, L;Wang, M; Thrap3 promotes osteogenesis by inhibiting the degradation of Runx2 FASEB journal : official publication of the Federation of American Societies for Experimental Biology [PMID: 35230719]

Bioinformatics

• Gene Symbol: THRAP3
• Uniprot:
  • Q9Y2W1(Human)