Species: Hu
Applications: WB, IHC, IP, ChIP, KD
Host: Rabbit Polyclonal
Species: Hu, Mu, Pm, Bv, Ca, Ch, Pm, Eq, Pm
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Thyroid hormone receptors (TRs) are ligand dependent members of the steroid/retinoic acid superfamily of transcription factors. The two genes encoding TRs identified to date, TR alpha and TR beta, have been mapped to human chromosomes 17 and 3, respectively. TRs bind to thyroid hormone response elements (TREs) with half site binding motifs in the orientation of palindromes, direct repeats, or inverted palindromes. The affinities of binding are both variable and influenced differentially by 3,5,3 triiodo L thyronine (T3). Thyroid hormones, through their interaction with the thyroid receptor (TR), effect metabolic processes, growth and development in many tissues by regulating the expression of genes for growth hormone, malic enzyme and several hepatic proteins.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
9967 |
| Alternate Names |
- FLJ22082
- MGC133082
- MGC133083
- thyroid hormone receptor associated protein 3
- Thyroid hormone receptor-associated protein complex 150 kDa component
- thyroid hormone receptor-associated protein, 150 kDa subunit
- Trap150
- TRAP150thyroid hormone receptor-associated protein 3
|
