THRAP3 Products

Description

Thyroid hormone receptors (TRs) are ligand dependent members of the steroid/retinoic acid superfamily of transcription factors. The two genes encoding TRs identified to date, TR alpha and TR beta, have been mapped to human chromosomes 17 and 3, respectively. TRs bind to thyroid hormone response elements (TREs) with half site binding motifs in the orientation of palindromes, direct repeats, or inverted palindromes. The affinities of binding are both variable and influenced differentially by 3,5,3 triiodo L thyronine (T3). Thyroid hormones, through their interaction with the thyroid receptor (TR), effect metabolic processes, growth and development in many tissues by regulating the expression of genes for growth hormone, malic enzyme and several hepatic proteins.

Bioinformatics

Entrez	9967 Human
Uniprot	Q9Y2W1 Human NP_005110 Human
Product By Gene ID	9967
Alternate Names	MGC133082 Trap150 FLJ22082 thyroid hormone receptor-associated protein, 150 kDa subunit Thyroid hormone receptor-associated protein complex 150 kDa component TRAP150thyroid hormone receptor-associated protein 3 MGC133083 thyroid hormone receptor associated protein 3

Diseases related to THRAP3

Discover more about diseases related to THRAP3.

Malignant Neoplasms
Neoplasms
Bone Neoplasms
Carcinoma
Bone Cysts, Aneurysmal
Dermatofibrosarcoma
Malignant Squamous Cell Neoplasm
Cell Transformation, Neoplastic
Dermatofibrosarcoma Protuberans
Liver Carcinoma
Hepatitis
Hepatitis B
Malignant Neoplasm Of Liver
Hepatocarcinogenesis
Carcinogenesis
Mouth Neoplasms
Osteosarcoma
Dysplasia
Chromosomal Translocation
Liver Neoplasms

Pathways for THRAP3

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Rna Processing
Cell Cycle
Dna Repair
Hypersensitivity

Research Areas for THRAP3

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Signal Transduction
Transcription Factors and Regulators

PTMs for THRAP3

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Phosphorylation

Bioinformatics Tool for THRAP3

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