Independent Antibodies: Western Blot: THRAP3 Antibody [NB100-40848] - Detection of Human THRAP3/TRAP150 on HeLa whole cell lysate using NB100-40848. THRAP3/TRAP150 was also immunoprecipitated by other rabbit ...read more
Immunohistochemistry-Paraffin: THRAP3 Antibody [NB100-40848] - Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti- THRAP3/TRAP150 used at a dilution of 1:1,000 (0.2ug/ml). ...read more
The immunogen recognized by this antibody maps to a region between residue 905 and the C-terminus (residue 955) of human Thyroid Hormone Receptor Associated Protein 3 using the numbering given in entry NP_005110.1 (GeneID 9967).
Immunogen affinity purified
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Use in chromatin immunoprecipitation reported in scientific literature (PMID 24819052). Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections. Knockdown validation (PMID: 31890047).
Read Publications using NB100-40848 in the following applications:
TRAP150thyroid hormone receptor-associated protein 3
Thyroid hormone receptors (TRs) are ligand dependent members of the steroid/retinoic acid superfamily of transcription factors. The two genes encoding TRs identified to date, TR alpha and TR beta, have been mapped to human chromosomes 17 and 3, respectively. TRs bind to thyroid hormone response elements (TREs) with half site binding motifs in the orientation of palindromes, direct repeats, or inverted palindromes. The affinities of binding are both variable and influenced differentially by 3,5,3 triiodo L thyronine (T3). Thyroid hormones, through their interaction with the thyroid receptor (TR), effect metabolic processes, growth and development in many tissues by regulating the expression of genes for growth hormone, malic enzyme and several hepatic proteins.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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