TGF-beta RI/ALK-5 Antibody (RM0016-3A11) - Azide and BSA Free

Immunohistochemistry-Paraffin: TGF-beta RI/ALK-5 Antibody (RM0016-3A11) [NBP2-11921] - Parrafin lung and kidney sections from LPS treated mice using anti ALK5 antibody.

• Reactivity: Mu
• Applications: WB, IHC
• Clone: RM0016-3A11
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

TGF-beta RI/ALK-5 Antibody (RM0016-3A11) - Azide and BSA Free Summary

• Immunogen: Mouse TGF-beta RI/ALK-5 (extracellular domain)
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Rat
• Gene: TGFBR1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50-100
  • Immunohistochemistry-Paraffin 1:50-1:100
  • Western Blot 1:800-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Alternate Names for TGF-beta RI/ALK-5 Antibody (RM0016-3A11) - Azide and BSA Free

• AAT5
• activin A receptor type II-like kinase, 53kD
• activin A receptor type II-like kinase, 53kDa
• Activin receptor-like kinase 5
• ACVRLK4
• ALK-5
• ALK-5ALK5
• EC 2.7.11
• EC 2.7.11.30
• LDS1A
• LDS2A
• Serine/threonine-protein kinase receptor R4
• SKR4
• tbetaR-I
• TGFB1R1
• TGF-beta receptor type I
• TGF-beta receptor type-1
• TGF-beta RI
• TGF-beta type I receptor
• TGFbetaRI
• TGFBR1
• TGF-bRI
• TGFR-1
• transforming growth factor beta receptor I
• transforming growth factor, beta receptor 1
• transforming growth factor, beta receptor I (activin A receptor type II-likekinase, 53kD)
• Transforming growth factor-beta receptor type I

Background

TGF beta Receptor I is encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TGFBR1
• Uniprot:
  • BAA05023()