Recombinant Human TGF-beta 1 Protein

Product Discontinued

Recombinant Human TGF-beta 1 Protein Summary

• Description: Recombinant bioactive protein for Human TGF-beta 1
  
  Source:CHO cells
  Amino Acid Sequence:(P01137)
  
  This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab285556)
• Preparation Method: Determined to be >98% pure by SDS-PAGE
• Details of Functionality: The ED50 as determined by the ability of TGF-B1 to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells is <0.05 ng/ml, corresponding to a specific activity of >2 x 107 units/mg.
• Source: CHO
• Protein/Peptide Type: Recombinant Protein
• Gene: TGFB1
• Purity: >98%, by SDS-PAGE
• Endotoxin Note: <0.1 ng/ug

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Theoretical MW: 25.0 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from sodium citrate buffer (pH 3.5)
• Concentration: Lyoph
• Purity: >98%, by SDS-PAGE
• Reconstitution Instructions: Reconstitution in H2O to 50 ug/ml will yield a solution of 1 mM citrate buffer (pH 3.5). The solution can then be stored at 4C for 1 month. Further dilutions should be made in PBS containing 2 mg/ml albumin and stored at -20C.

Alternate Names for Recombinant Human TGF-beta 1 Protein

• CEDLAP
• DPD1
• latency-associated peptide
• TGF beta
• TGF beta1
• TGFB
• TGFB1
• TGF-beta 1 protein
• TGFbeta 1
• TGF-beta 1
• TGFbeta
• TGF-beta-1
• transforming growth factor beta-1
• transforming growth factor, beta 1

Background

TGF-Beta 1 (Transforming Growth Factor-Beta 1) is a member of the superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF-Beta 1 is a 25.0 kDa protein containing two identical 112 amino acid polypeptide chains linked by a single disulfide bond.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: TGFB1