TGF-beta 1 Antibody

Images

 
Western Blot: TGF-beta 1 Antibody [NBP1-45891] - Mouse 3T3 cell lysate with TGF-beta 1 antibody.
Immunocytochemistry/ Immunofluorescence: TGF-beta 1 Antibody [NBP1-45891] - Co-localization of F4/80+ and TGF-B1 at tendon injury site 1 week after burn/tenotomy. Scale bars correspond to 100um. d Left: Co-localization ...read more
TGF-beta1 expressing macrophages are present during HO formation.a Left: GSEA analysis of microarray data collected from buffy coat of human burn injury patients at increased risk of HO compared to post-surgical control ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, PoSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

TGF-beta 1 Antibody Summary

Description
This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab92486)
Immunogen
Synthetic peptide surrounding amino acid 374 of human TGF beta 1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TGFB1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 0.5 - 4 ug/mL
Application Notes
Use in Immunocytochemistry/Immunofluorescence reported in scientific literature (PMID:32024825).
Reviewed Applications
Read 1 Review rated 5
using
NBP1-45891 in the following applications:

Publications
Read Publications using
NBP1-45891 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2), 0.5% BSA, 30% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for TGF-beta 1 Antibody

  • CEDLAP
  • DPD1
  • latency-associated peptide
  • TGF beta
  • TGF beta1
  • TGFB
  • TGFB1
  • TGF-beta 1 protein
  • TGFbeta 1
  • TGF-beta 1
  • TGFbeta
  • TGF-beta-1
  • transforming growth factor beta-1
  • transforming growth factor, beta 1

Background

Transforming growth factor betas (TGFbetas) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFalpha. It is now realized that TGFbetas mediate many cell-cell interactions that occur during embryonic development. Three TGFbetas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFbeta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFbeta3 protein has approximately 80% identity to the mature region of both TGFbeta1 and TGFbeta2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP1-45891
Species: Hu, Mu, Rt, Po
Applications: WB, ICC/IF
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for TGF-beta 1 Antibody (NBP1-45891)(7)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 3 applications: ICC/IF, IHC-Fr, WB.


Filter By Application
ICC/IF
(2)
IHC-Fr
(1)
WB
(2)
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Mouse
(3)
All Species

Review for TGF-beta 1 Antibody (NBP1-45891) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Mouse.

Reviews using NBP1-45891:
Filter by Applications
IHC-P
(1)
All Applications
Filter by Species
Mouse
(1)
All Species
Images Ratings Applications Species Date Details
  5
reviewed by:
Charles Hwang
IHC-P Mouse 07/11/2017
View

Summary

ApplicationImmunohistochemistry-Paraffin
Sample TestedMouse tissue
SpeciesMouse
Lot1G15559

Comments

CommentsParaffin sections
Citrate 6.0 HIER 30min + 20min cooled at RT
AF488 and AF594

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TGF-beta 1 Antibody (NBP1-45891) (0)

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Secondary Antibodies

 

Isotype Controls

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Diseases for TGF-beta 1 Antibody (NBP1-45891)

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Research Areas for TGF-beta 1 Antibody (NBP1-45891)

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Blogs on TGF-beta 1.

TGF-beta 1 - a versatile signaling molecule with roles in development and disease
The transforming growth factor-beta (TGF-beta) family consists of a wide variety of signaling proteins with roles in development. TGF-beta signaling controls growth, differentiation, and immune responses and is often misregulated in cancer. TGF-beta ...  Read full blog post.

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Recent Reviews

5
5
1
4
0
3
0
2
0
1
0

 
Charles Hwang
07/11/2017
Application: IHC-P
Species: Mouse

Bioinformatics

Gene Symbol TGFB1
Entrez
Uniprot