TGF-beta 1 Antibody Pair [HRP] Summary
| Description |
Solid Phase sandwich ELISA for the quantitative determination of Human TGF-beta 1. |
| Specificity |
This solid phase sandwich ELISA utilizes an antibody specific for Human TGF-beta 1. |
| Standard Curve Range |
39.06-2500 pg/ml (example only; lot dependent) |
| Sensitivity |
39.06 pg/ml |
| Assay Type |
Sandwich ELISA |
| Sample Volume |
100 ul |
| Gene |
TGFB1 |
Applications/Dilutions
Packaging, Storage & Formulations
| Storage |
Storage is content dependent. |
Kit Components
|
Components
|
- Capture Antibody
- Detection Antibody
- Standard
|
Alternate Names for TGF-beta 1 Antibody Pair [HRP]
Background
TGF-beta-1 is a multifunctional cytokine that belongs to a superfamily of structurally related regulatory proteins, which includes three mammalian TGF-beta isoforms (TGF-beta-1, -beta-2, and -beta-3), activin/inhibins and bone morphogenetic proteins. The most abundant isoform, TGF-beta-1, is a 25kDa homodimer composed of two 12.5kDa subunits joined by disulfide bonds. TGF-beta-1 is a highly conserved molecule - the amino acid sequence between human and mouse differ only by one residue. Although originally defined by its ability to cause anchorage independent cell growth and changes in cell morphology of rat fibroblasts, subsequent research has revealed that TGF-beta is actually a major growth inhibitor for most cell types. It is produced by a wide variety of cell and tissue types during all stages of cell differentiation. TGF-beta-1 sources include platelets, bone and soft tissues such as placenta and kidneys.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are
guaranteed for 6 months from date of receipt.
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