Western Blot: Neurotensin Receptor 2 Antibody [NB100-56472] - Analysis of neurotensin receptor 2 in the 1) absence and 2) presence of immunizing peptide in mouse brain lysate using this antibody at 2 ug/ml.
Immunohistochemistry-Paraffin: Neurotensin Receptor 2 Antibody [NB100-56472] - Analysis of human brain, cerebellum using this antibody at 10 ug/ml.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.2% gelatin
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified
Alternate Names for NTS2/NTSR2 Antibody - BSA Free
neurotensin receptor 2
neurotensin receptor type 2
neurotensin receptor, type 2
NT-R-2
NTR2Levocabastine-sensitive neurotensin receptor
NTS2
NTSR2
Background
Official Gene Symbol: NTSR2 Gen Bank Accession Number: NP_036476 Gene ID: 23620 (Human) Gene Map Locus: 2p25.1 (Human) NTR2 is a member of GPCR family. It contains a short N-terminal sequence, 7 transmembrane domains and a short cytoplasmic tail. It is a low affinity levocabastine-sensitive receptor for Neurotensin. Activation of NT2R by non-peptide agonists suggests that the receptor can couple to phospholipase C, phospholipase A2 and MAPK. Unlike NTR1, NTR2 is insensitive to GTP and has low sensitivity of sodium ions. Northern Blot analysis detected its expression in adult brain regions including the olfactory system, cerebral and crebellar cortices, hippocampus and hypothalamic nuclei. Its expression has also been found in low levels in kidney, uterus, heart and lung.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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