PTH1R/PTHR1 Antibody (3D1.1)

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Immunohistochemistry-Paraffin: PTH1R/PTHR1 Antibody (3D1.1) [NBP1-40067] - Analysis of anti-PTH1R antibody with human liver at concentration 5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, Po, Bv, Ca, Eq, Mk, Pm, Rt, Bt, Ch, Ha, Op, RbSpecies Glossary
Applications WB, ICC/IF, IHC-P
Clone
3D1.1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

PTH1R/PTHR1 Antibody (3D1.1) Summary

Immunogen
Synthetic peptide corresponding to aa146-169 of human PTH/PTHrP Receptor [RRCDRNGSWELVPGHNRTWANYSE]. Species sequence Homology: Mouse & rat (23/24aa).
Specificity
Recognizes human PTH/PTHrP receptor, MW 80kD, and the receptor dimer, Mr 160kD. A faint nonspecific band at 110kD is also detected. This antibody does not detect the PTH2 receptor.
Predicted Species
Rat (96%), Rabbit (96%), Bat (96%), Opossum (92%), Hamster (96%), Chicken (92%). Backed by our 100% Guarantee.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PTH1R
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.5-2 ug/ml
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Paraffin 5 ug/ml
Application Notes
Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 28727763).
Publications
Read Publications using
NBP1-40067 in the following applications:

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 28727763). Gorilla, Orangutan, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (96%), Xenopus (88%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.6) and 30% Glycerol
Preservative
0.07% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for PTH1R/PTHR1 Antibody (3D1.1)

  • MGC138426
  • parathyroid hormone 1 receptorMGC138452
  • parathyroid hormone/parathyroid hormone-related peptide receptor
  • parathyroid hormone/parathyroid hormone-related protein receptor
  • PFE
  • PTH/PTHr receptor
  • PTH/PTHrP type I receptor
  • PTH1 receptor
  • PTH1R
  • PTHR
  • PTHR1
  • PTHRPTHR1parathyroid hormone receptor 1
  • seven transmembrane helix receptor

Background

PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR. PTHR1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus. ESTs have been isolated from B-cell/lung/testis, brain, breast, fetus, heart, heart/melanocyte/uterus, kidney, liver/spleen, lung, placenta, and testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: WB, ICC/IF, IHC-P

Publications for PTH1R/PTHR1 Antibody (NBP1-40067)(2)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: ICC/IF, WB.


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ICC/IF
(1)
WB
(1)
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Mouse
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Diseases for PTH1R/PTHR1 Antibody (NBP1-40067)

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Bioinformatics

Gene Symbol PTH1R
Entrez
Uniprot