TBP like protein TLP Antibody

Product Discontinued

TBP like protein TLP Antibody Summary

• Immunogen: TBPL1 (NP_004856, 1 a.a. ~ 92 a.a) partial recombinant protein with GST tag.MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKL
• Specificity: TBPL1 - TBP-like 1
• Clonality: Polyclonal
• Host: Mouse
• Gene: TBPL1
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: The quality control of this antibody is limited to Western blot on the immunizing protein. It has also been used for ELISA. Abnova's recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Unpurified antisera so the specific antibody concentration is unknown. Contains 50% glycerol.
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TBP like protein TLP Antibody

• 21 kDa TBP-like protein
• STUD21-kDA TBP-like protein
• TATA box binding protein-related factor 2
• TATA box-binding protein-like protein 1
• TATA box-binding protein-related factor 2
• TBP-like 1
• TBP-like factor
• TBP-like protein 1
• TBP-related factor 2
• TBP-related protein
• TLFMGC:8389
• TLP21
• TLPMGC:9620
• TRF2Second TBP of unique DNA protein
• TRP

Background

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TBPL1
• Entrez:
  • 9519(Human)
• OMIM:
  • 605521(Human)
• Uniprot:
  • NP_004856(Human)