Talin1 Antibody (93E12) - BSA Free

• Reactivity: Mu
• Applications: WB, ELISA, ICC/IF, IHC, IP
• Clone: 93E12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Talin1 Antibody (93E12) - BSA Free Summary

• Description: Novus Biologicals Mouse Talin1 Antibody (93E12) - BSA Free (NBP2-50319) is a monoclonal antibody validated for use in IHC, WB, ELISA, ICC/IF and IP. Anti-Talin1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein fragment
• Specificity: Does not cross react with Talin2.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: TLN1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:500
  • Immunohistochemistry
  • Immunoprecipitation 1:10 - 1:500
  • Western Blot 1:100 - 1:2000
• Application Notes: Positive control(s): fibroblasts.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for Talin1 Antibody (93E12) - BSA Free

• ILWEQ
• KIAA1027
• talin 1
• Talin1
• talin-1
• TLN
• TLN1

Background

Talin 1 encodes a cytoskeletal protein which is concentrated in areas of cell-substratum and cell-cell contacts. This protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Talin1 Antibody (NBP2-50319)(1)

Publication using NBP2-50319

• Lagarrigue F, Gingras AR, Paul DS et al. Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation. Blood Adv 2018-09-25 [PMID: 30242097] (WB, Mouse)

Bioinformatics

• Gene Symbol: TLN1