Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Goat Polyclonal
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
Talin 1 encodes a cytoskeletal protein which is concentrated in areas of cell-substratum and cell-cell contacts. This protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.
Bioinformatics
| Entrez |
Mouse
Rat
Chicken
Human
|
| Uniprot |
Human
Human
Human
Human
Chicken
Human
|
| Product By Gene ID |
7094 |
| Alternate Names |
- ILWEQ
- KIAA1027
- talin 1
- talin-1
- TLN
|
Research Areas for Talin1
Find related products by research area and learn more about each of the different research areas below.
Cytoskeleton Markers
![Western Blot Talin1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Talin1_AF5456_Western_Blot_5726.jpg)
![Western Blot Talin1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/af5456_human-mouse-rat-talin1-affinity-purified-polyclonal-ab-western-blot-21520259259..jpg)
