Syndecan-4 Antibody

Western Blot: Syndecan-4 Antibody [NBP2-24630] - Analysis of Syndecan 4 in Jurkat cell lysate in the 1) absence and 2) presence of immunizing peptide and 3) Raw cell lysate using NBP2-24630 at 1.0 ug/ml.

• Reactivity: Hu, Mu, Pm, Pm, Eq, Pm
• Applications: WB, Simple Western
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 1.0 mg/ml

Syndecan-4 Antibody Summary

• Description: Novus Biologicals Rabbit Syndecan-4 Antibody (NBP2-24630) is a polyclonal antibody validated for use in WB and Simple Western. Anti-Syndecan-4 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A portion of amino acids 1-50 of human Syndecan-4 was used as the immunogen.
• Marker: Plasma Membrane Marker
• Predicted Species: Chimpanzee (100%), Monkey (100%), Equine (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SDC4
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Simple Western 1:10
  • Western Blot 1-2 ug/ml
• Application Notes: See Simple Western Antibody Database for Simple Western validation: Tested in 12Z, Ovaries, separated by Size, antibody dilution of 1:10

Reactivity Notes

The amino acid sequence used as immunogen is 85% homologous in Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A purified

Alternate Names for Syndecan-4 Antibody

• Amphiglycan
• MGC22217
• Ryudocan core protein
• Ryudocan
• SDC4
• SYND4ryudocan amphiglycan
• syndecan 4 (amphiglycan, ryudocan)
• syndecan 4
• syndecan proteoglycan 4
• Syndecan4
• Syndecan-4

Background

Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 is an matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan-1 and Syndecan-3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan-2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan-4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Syndecan-4 Antibody (NBP2-24630)(1)

Publication using NBP2-24630

• Ponandai-Srinivasan S, Saare M, et al. Syndecan-1 modulates the invasive potential of endometrioma via TGF-beta signalling in a subgroup of women with endometriosis. Hum Reprod 2020-10-01 [PMID: 32897364] (Simple Western, Human)

Bioinformatics

• Gene Symbol: SDC4