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Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 is an matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan-1 and Syndecan-3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan-2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan-4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.
![Immunocytochemistry Syndecan-4 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/Syndecan4_AF2918_Immunocytochemistry__Immunofluorescence_17413.jpg)
![N/A Syndecan-4 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_Syndecan4_DY2918_ELISA_1896.jpg)
