Syndecan-2/CD362 Antibody [DyLight 550]

• Reactivity: Mu
• Applications: Flow, CyTOF-ready
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: DyLight 550

Syndecan-2/CD362 Antibody [DyLight 550] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Syndecan-2/CD362
  Glu19-Phe141
  Accession # P43407
• Specificity: Detects mouse Syndecan-2/CD362 in direct ELISAs. In direct ELISAs, less than 1% cross-reactivity with recombinant human Syndecan-2/CD362 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: SDC2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product AF6585. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Syndecan-2/CD362 Antibody [DyLight 550]

• CD362 antigen
• CD362
• Fibroglycan
• heparan sulfate proteoglycan 1, cell surface-associated
• Heparan sulfate proteoglycan core protein
• HSPG
• HSPG1
• HSPG1syndecan proteoglycan 2
• SDC2
• SYND2
• SYND2cell surface-associated heparan sulfate proteoglycan 1
• syndecan 2
• Syndecan2
• Syndecan-2

Background

Proteoglycans are macromolecules consisting of a variety of core proteins with covalently attached one or several polysaccharide chains of the glycosaminoglycan type (heparan sulphate, heparin, chondroitin sulphate, dermatan sulphate or keratan sulphate). At least two forms of basement membrane heparan sulphate proteoglycan (HSPG) have been identified. One with a large core protein (> 400 kD) and one with a small core protein (30 kD). The large HSPG is probably the most abundant basement membrane proteoglycan. It is located predominantly in the lamina lucida, where it forms clustered aggregates and interacts with other basement membrane components to form the matrix. In addition, it also plays a critical role in attachment of cells to the basal membrane via integrin receptors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SDC2