Syndecan-2/CD362 Products

Description

Proteoglycans are macromolecules consisting of a variety of core proteins with covalently attached one or several polysaccharide chains of the glycosaminoglycan type (heparan sulphate, heparin, chondroitin sulphate, dermatan sulphate or keratan sulphate). At least two forms of basement membrane heparan sulphate proteoglycan (HSPG) have been identified. One with a large core protein (> 400 kD) and one with a small core protein (30 kD). The large HSPG is probably the most abundant basement membrane proteoglycan. It is located predominantly in the lamina lucida, where it forms clustered aggregates and interacts with other basement membrane components to form the matrix. In addition, it also plays a critical role in attachment of cells to the basal membrane via integrin receptors.

Bioinformatics

Entrez	6383 Human
Uniprot	AAH49836 Human AAH49836.1 Human NP_002989 Human NP_002989.2 Human
Product By Gene ID	6383
Alternate Names	CD362 antigen Fibroglycan fibroglycan heparan sulfate proteoglycan 1, cell surface-associated Heparan sulfate proteoglycan core protein HSPG HSPG1syndecan proteoglycan 2 SYND2cell surface-associated heparan sulfate proteoglycan 1 syndecan 2 syndecan-2

Research Areas for Syndecan-2/CD362

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Extracellular Matrix