Synaptopodin Antibody (918842) [Janelia Fluor® 646]

• Reactivity: Hu
• Applications: IHC
• Clone: 918842
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 646

Synaptopodin Antibody (918842) [Janelia Fluor® 646] Summary

• Immunogen: E. coli-derived recombinant human Synaptopodin
  Ser363-Gln490
  Accession # Q8N3V7
• Specificity: Detects human Synaptopodin in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: SYNPO
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Synaptopodin Antibody (918842) [Janelia Fluor® 646]

• KIAA1029
• Synaptopodin
• SYNPO

Background

Synaptopodin, a prolin-rich actin-binding protein with 2 binding sites for actin, represents a new class of actin-binding proteins which has first been localized in podocytes and a subset of telencephalic postsynaptic densities. In human tissue synaptopodin has a molecular weight of 73.7 kD and pI of 9.38 (calculated from sequence data); in mouse the corresponding data are 74 kD, pI 9.27. In SDS-PAGE the antigen appears as 100 kD polypeptide in brain and 110 kD polypeptide in kidney (the difference might be attributed to posttranslational modifications).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SYNPO