Synaptopodin Antibody (918842) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: IHC
• Clone: 918842
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

Synaptopodin Antibody (918842) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human Synaptopodin
  Ser363-Gln490
  Accession # Q8N3V7
• Specificity: Detects human Synaptopodin in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Synaptopodin Antibody (918842) [Alexa Fluor® 488]

• KIAA1029
• Synaptopodin
• SYNPO

Background

Synaptopodin is a 929 amino acid, actin associated protein with restricted expression in brain and kidney.  First reported in glomerular podocytes, the protein is also  found in postsynaptic densities (PSDs) in a subpopulation of telencephalic neurons where it is thought to participate in synaptic plasticity in dendritic spines.  Despite its localization in PSDs, it is not homologous to other PSD proteins.  Loss of synaptopodin expression has been demonstrated in Alzheimer’s patients. In glomeruli, synaptopodin localizes to the cytoplasm of podocyte foot processes. 

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.