Sulfatase Modifying Factor 2/SUMF2 Antibody

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

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Sulfatase Modifying Factor 2/SUMF2 Antibody Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Sulfatase Modifying Factor 2/SUMF2
Gln34-Leu308
Accession # Q8BPG6
Specificity
Detects mouse Sulfatase Modifying Factor 2/SUMF2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human (rh) SUMF2 and less than 5% cross-reactivity with rhSUMF1 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
SUMF2
Purity
Immunogen affinity purified
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
  • Immunoprecipitation 25 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Immunogen affinity purified
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Sulfatase Modifying Factor 2/SUMF2 Antibody

  • C-alpha-formyglycine-generating enzyme 2
  • C-alpha-formylglycine-generating enzyme 2
  • DKFZp566I1024
  • DKFZp686I1024
  • DKFZp686L17160
  • DKFZp781L1035
  • FGE2
  • MGC99485
  • paralog of the formylglycine-generating enzyme
  • pFGE
  • sulfatase modifying factor 2
  • sulfatase-modifying factor 2
  • SUMF2

Background

Mouse SUMF2 is a 30 kDa member of the sulfatase-modifying factor family. It is synthesized as a 275 amino acid (aa) glycoprotein that is localized to the ER. It contains multiple calcium-binding sites and three (sub)domains of varying length and ill-defined structure (aa 38‑298). There is one potential alternate start site at aa 118 that would generate a 190 aa precursor. The founding family member, SUMF1, posttranslationally activates newly synthesized sulfatases by converting a Cysteine to formylGly in the catalytic site. SUMF2 apparently has no such activity. It forms homodimers and heterodimers with SUMF1. As a heterodimer, it downmodulates SUMF1 activity. Mature mouse SUMF2 is 85% and 93% aa identical to human and rat SUMF2, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SUMF2
Uniprot