Sulfatase Modifying Factor 2/SUMF2 Antibody [Janelia Fluor® 669]

• Reactivity: Mu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Janelia Fluor 669

Sulfatase Modifying Factor 2/SUMF2 Antibody [Janelia Fluor® 669] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Sulfatase Modifying Factor 2/SUMF2
  Gln34-Leu308
  Accession # Q8BPG6
• Specificity: Detects mouse Sulfatase Modifying Factor 2/SUMF2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human (rh) SUMF2 and less than 5% cross-reactivity with rhSUMF1 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SUMF2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Sulfatase Modifying Factor 2/SUMF2 Antibody [Janelia Fluor® 669]

• C-alpha-formyglycine-generating enzyme 2
• C-alpha-formylglycine-generating enzyme 2
• DKFZp566I1024
• DKFZp686I1024
• DKFZp686L17160
• DKFZp781L1035
• FGE2
• MGC99485
• paralog of the formylglycine-generating enzyme
• pFGE
• sulfatase modifying factor 2
• sulfatase-modifying factor 2
• SUMF2

Background

The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SUMF2