Sulfatase Modifying Factor 2/SUMF2 Products

Antibodies
Sulfatase Modifying Factor 2/ ...
Sulfatase Modifying Factor 2/SUMF2...
NBP1-84145
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Sulfatase Modifying Factor 2/ ...
Sulfatase Modifying Factor 2/SUMF2...
AF2779
Species: Hu
Applications: WB, IP
Host: Goat Polyclonal
Sulfatase Modifying Factor 2/ ...
Sulfatase Modifying Factor 2/SUMF2...
AF3454
Species: Mu
Applications: WB, IP
Host: Goat Polyclonal
Lysates
Sulfatase Modifying Factor 2/ ...
Sulfatase Modifying Factor 2/SUMF2...
NBP2-07177
Applications: WB
Proteins
Recombinant Human Sulfatase M ...
Recombinant Human Sulfatase Modify...
H00025870-Q01
Species: Hu
Applications: WB, ELISA, PA
Sulfatase Modifying Factor 2/ ...
Sulfatase Modifying Factor 2/SUMF2...
NBP1-84145PEP
Species: Hu
Applications: AC
RNAi
Sulfatase Modifying Factor 2/ ...
Sulfatase Modifying Factor 2/SUMF2...
H00025870-R02
Species: Hu
Applications: RNAi, RNAi SP
Sulfatase Modifying Factor 2/ ...
Sulfatase Modifying Factor 2/SUMF2...
H00025870-R04
Species: Hu
Applications: RNAi, RNAi SP
Sulfatase Modifying Factor 2/ ...
Sulfatase Modifying Factor 2/SUMF2...
H00025870-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 25870
Alternate Names
  • sulfatase-modifying factor 2
  • paralog of the formylglycine-generating enzyme
  • MGC99485
  • pFGE
  • DKFZp781L1035
  • C-alpha-formyglycine-generating enzyme 2
  • DKFZp686L17160
  • DKFZp686I1024
  • C-alpha-formylglycine-generating enzyme 2
  • DKFZp566I1024
  • sulfatase modifying factor 2

Diseases related to Sulfatase Modifying Factor 2/SUMF2

Discover more about diseases related to Sulfatase Modifying Factor 2/SUMF2.

Multiple Sulfatase Deficiency Disease
Deficiency Of Sulfatase
Lysosomal Storage Diseases
Sphingolipidoses
Crohn Disease
Inflammation
Noma
Storage Disease

Pathways for Sulfatase Modifying Factor 2/SUMF2

View related products by pathway and learn more about each of the pathways below.

Secretion
Mrna Transcription
Glycosylation
Interleukin-13 Secretion
Localization

PTMs for Sulfatase Modifying Factor 2/SUMF2

Learn more about PTMs related to Sulfatase Modifying Factor 2/SUMF2.

Oxidation
Glycosylation

Bioinformatics Tool for Sulfatase Modifying Factor 2/SUMF2

Discover related pathways, diseases and genes to Sulfatase Modifying Factor 2/SUMF2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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