Sulfatase Modifying Factor 1/SUMF1 Antibody [Unconjugated] Summary
Immunogen |
Mouse myeloma cell line NS0-derived recombinant human SUMF1 isoform 1 Ser34-Asp374 with a Ser63Asn substitution Accession # Q8NBK3 |
Specificity |
Detects human SUMF1 in direct ELISAs and Western blots. In these formats, approximately 45% cross-reactivity with recombinant mouse SUMF1 is observed and less than 1% cross-reactivity with recombinant human SUMF2 is observed.
|
Source |
N/A |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Goat |
Gene |
SUMF1 |
Purity |
Immunogen affinity purified |
Purity Statement |
Antigen Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
|
Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative |
No Preservative |
Concentration |
LYOPH |
Purity |
Immunogen affinity purified |
Reconstitution Instructions |
Reconstitute at 0.2 mg/mL in sterile PBS. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Sulfatase Modifying Factor 1/SUMF1 Antibody [Unconjugated]
Background
Human SUMF-1 (also FGE) is a 42 kDa (341 aa), Ca++-binding
member of the sulfatase-modifying factor family. It is a soluble ER
lumenal glycoprotein that converts inactive sulfatases into an active
form by transforming a catalytic site cysteine into a formylglycine
residue. In the ER, SUMF-1 can exist as either a monomer, or a
disulfide-linked homodimer or a heterodimer with SUMF-2. Three splice
isoforms are known. Mature human SUMF-1 shares 90% aa sequence identity
with mouse SUMF-1.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for Sulfatase Modifying Factor 1/SUMF1 Antibody (AF3680) (0)
Secondary Antibodies
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Isotype Controls
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