Sulfatase Modifying Factor 1/SUMF1 Products

Antibodies
Sulfatase Modifying Factor 1/ ...
Sulfatase Modifying Factor 1/SUMF1...
NBP1-83905
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Sulfatase Modifying Factor 1/ ...
Sulfatase Modifying Factor 1/SUMF1...
AF3680
Species: Hu
Applications: WB
Host: Goat Polyclonal
Sulfatase Modifying Factor 1/ ...
Sulfatase Modifying Factor 1/SUMF1...
MAB2779
Species: Hu, Mu
Applications: WB, IP
Host: Mouse Monoclonal
Lysates
Sulfatase Modifying Factor 1/ ...
Sulfatase Modifying Factor 1/SUMF1...
NBL1-16610
Applications: WB
Proteins
Sulfatase Modifying Factor 1/ ...
Sulfatase Modifying Factor 1/SUMF1...
H00285362-Q01
Species: Hu
Applications: WB, ELISA, PA
Sulfatase Modifying Factor 1/ ...
Sulfatase Modifying Factor 1/SUMF1...
NBP1-83905PEP
Species: Hu
Applications: AC
Sulfatase Modifying Factor 1/ ...
Sulfatase Modifying Factor 1/SUMF1...
NBP1-72540
Species: Hu
Applications: PAGE

Description

Sulfatases catalyze the hydrolysis of sulfate esters such as glycosaminoglycans, sulfolipids, and steroid sulfates. C-alpha-formylglycine (FGly), the catalytic residue in the active site of eukaryotic sulfatases, is posttranslationally generated from a cysteine by SUMF1, the FGly-generating enzyme (FGE), in the endoplasmic reticulum (ER). The genetic defect of FGly formation caused by mutations in the SUMF1 gene results in multiple sulfatase deficiency (MSD; MIM 272200), a lysosomal storage disorder (Roeser et al., 2006 [PubMed 16368756]).[supplied by OMIM]

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 285362
Alternate Names
  • EC 1.8.99.-
  • MGC131853
  • sulfatase-modifying factor 1
  • AAPA3037
  • FGly-generating enzyme
  • UNQ3037
  • FGEC-alpha-formylglycine-generating enzyme 1
  • MGC150436
  • sulfatase modifying factor 1

PTMs for Sulfatase Modifying Factor 1/SUMF1

Learn more about PTMs related to Sulfatase Modifying Factor 1/SUMF1.

Oxidation
Glycosylation
Phosphorylation

Bioinformatics Tool for Sulfatase Modifying Factor 1/SUMF1

Discover related pathways, diseases and genes to Sulfatase Modifying Factor 1/SUMF1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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