Sulfatase Modifying Factor 1/SUMF1 Antibody (329005)

• Reactivity: Hu, Mu
• Applications: WB, IP
• Clone: 329005
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

Sulfatase Modifying Factor 1/SUMF1 Antibody (329005) Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Sulfatase Modifying Factor 1/SUMF1 isoform 1
  Ser34-Asp374 (Ser63Asn)
  Accession # Q8NBK3.3
• Specificity: Detects recombinant human or mouse Sulfatase Modifying Factor 1/SUMF1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human SUMF2 or recombinant mouse SUMF2 is observed.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: SUMF1
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 25 ug/mL
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Sulfatase Modifying Factor 1/SUMF1 Antibody (329005)

• AAPA3037
• EC 1.8.99.-
• FGE1
• FGEC-alpha-formylglycine-generating enzyme 1
• FGly-generating enzyme
• MGC131853
• MGC150436
• sulfatase modifying factor 1
• sulfatase-modifying factor 1
• SUMF1
• UNQ3037

Background

Also known as C-alpha -formylglycine-generating enzyme (FGE), SUMF1 converts the active site Cys residue of sulfatases into formylglycine, which is essential for sulfatase activity. SUMF1 defect causes multiple sulfatase deficiency (MSD). The amino acid sequence of rhSUMF1 is 93%, 92% and 90% identical to that of canine, bovine, and mouse/rat.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SUMF1
• Uniprot:
  • Q8NBK3.3()