STARD10 Antibody

Images

 

Product Details

Summary
Product Discontinued
View other related STARD10 Primary Antibodies

Order Details


    • Catalog Number
      NBP2-78818
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

STARD10 Antibody Summary

Immunogen
Full length recombinant human STARD10 protein (amino acids 1-291) [UniProt Q9Y365]
Clonality
Polyclonal
Host
Rabbit
Gene
STARD10
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 - 0.7 ug/ml
  • Immunocytochemistry/Immunofluorescence 1 - 3 ug/ml
  • Immunohistochemistry 1:200 - 1:400
  • Immunohistochemistry-Paraffin 1:200 - 1:400

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for STARD10 Antibody

  • Antigen NY-CO-28
  • CGI-52
  • MGC14401
  • NY-CO-28
  • PCTP2
  • PCTP-L
  • PCTP-like protein
  • Serologically defined colon cancer antigen 28SDCCAG28
  • StARD10
  • StAR-related lipid transfer (START) domain containing 10
  • StAR-related lipid transfer protein 10
  • START domain containing 10
  • START domain-containing protein 10

Background

STARD10, STAR-related lipid transfer protein 10 or PCTP-like (33 kDa) is a transporter for lipids which specifically shuttles phosphatidylcholine and phosphatidylethanolamine between membranes. Mammalian STARD10 belongs to a family of fifteen START-domain proteins. In these family members, the carboxy terminal START-domain is conserved and functions in lipid binding or as a lipid sensing domain. The specificity for the type of lipid bound differs among family members (e.g., STARD1,3,5 binds Cholesterol, STARD5 binds 25-hydroxycholesterol, STARD2 binds phosphatidylcholine, and STARD11 binds ceramides). STARD proteins have been associated with various cellular processes such as lipid trafficking, lipid metabolism, and cell signaling (1, 2).

STARD10 is broadly expressed in different organs and tissues such as the brain, endocrine tissues, liver, and gastrointestinal tract. STARD10 is regulated by Casein kinase II, which phosphorylates STARD10 at serine 284 leading to decreased lipid transfer activity and reduced membrane association. STARD10 is overexpressed in breast carcinoma cell lines and in primary breast cancers (3). STARD10 has been implicated in the regulation of bile acid homeostasis and more recently in the regulation of insulin secretion from beta-cells (1, 2, 4).

References

1. Alpy, F., & Tomasetto, C. (2005). Give lipids a START: The StAR-related lipid transfer (START) domain in mammals. Journal of Cell Science. https://doi.org/10.1242/jcs.02485

2. Alpy, F., Legueux, F., Tomasetto, C., & Bianchetti, L. (2009). START domain-containing proteins: A review of their role in lipid transport and exchange. Medecine/Sciences. https://doi.org/10.1051/medsci/2009252181

3. Olayioye, M. A., Hoffmann, P., Pomorski, T., Armes, J., Simpson, R. J., Kemp, B. E.,... Visvader, J. E. (2004). The phosphoprotein StarD10 is overexpressed in breast cancer and cooperates with ErbB receptors in cellular transformation. Cancer Research. https://doi.org/10.1158/0008-5472.CAN-03-3731

4. Carrat, G. R., Hu, M., Nguyen-Tu, M. S., Chabosseau, P., Gaulton, K. J., van de Bunt, M.,... Rutter, G. A. (2017). Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice. American Journal of Human Genetics. https://doi.org/10.1016/j.ajhg.2017.01.011

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-33485
Species: Hu, Mu, Po
Applications: WB, ICC/IF, IHC, IHC-P
H00058488-M01
Species: Hu
Applications: WB, ELISA, RNAi, S-ELISA
NBP2-99299
Species: Hu
Applications: WB, ICC/IF
MAB6860
Species: Hu
Applications: WB, IP
NBP1-31118
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-31376
Species: Hu, Rt
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IHC-P
AF1280
Species: Mu
Applications: WB, Simple Western, IHC
NB400-106
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-92448
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-68884
Species: Hu
Applications: WB
NBP2-37578
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF
H00005241-M08
Species: Hu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, S-ELISA
NBP1-69368
Species: Hu
Applications: WB, IHC, IHC-P
NBP2-33950
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-36987
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
NBP1-89228
Species: Hu
Applications: ICC/IF, IHC, IHC-P

Publications for STARD10 Antibody (NBP2-78818) (0)

There are no publications for STARD10 Antibody (NBP2-78818).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for STARD10 Antibody (NBP2-78818) (0)

There are no reviews for STARD10 Antibody (NBP2-78818). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for STARD10 Antibody (NBP2-78818) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Additional STARD10 Products

Bioinformatics Tool for STARD10 Antibody (NBP2-78818)

Discover related pathways, diseases and genes to STARD10 Antibody (NBP2-78818). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for STARD10 Antibody (NBP2-78818)

Discover more about diseases related to STARD10 Antibody (NBP2-78818).
 

Pathways for STARD10 Antibody (NBP2-78818)

View related products by pathway.

PTMs for STARD10 Antibody (NBP2-78818)

Learn more about PTMs related to STARD10 Antibody (NBP2-78818).

Blogs on STARD10

There are no specific blogs for STARD10, but you can read our latest blog posts.
Coronavirus Brochure

Contact Information

Learn the difference between western blot and simple western

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our STARD10 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol STARD10