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Immunogen affinity purified
This SR-BI antibody is useful for Flow cytometry (PMID 23029167), Western blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry paraffin embedded sections and Immunoprecipitation. In Western blot a band is observed at ~ 82 kDa in tissues that express SR-BI such as liver, ovary and adrenals and to a lesser extent testis, heart and mammary gland.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
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Mouse, rat, mink, hamster, primate, rabbit and the long form of human SR-BI. Reactivity with CHO cells reported in scientific literature (PMID: 12356718).
Alternate Names for SR-BI Antibody [DyLight 550]
CD36 and LIMPII analogous 1
CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1
CD36L1scavenger receptor class B type 1
CLA1 CD36 antigen-like 1
Collagen type I receptor, thrombospondin receptor-like 1
scavenger receptor class B type III
scavenger receptor class B, member 1
SRB1 scavenger receptor class B member 1
SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
ABCA1 (ATP-binding cassette transporter A1) The ABCA1 molecule is a primary gatekeeper for regulating the intracellular transport of cholesterol. It belongs to a larger related multifamily of cAMP-dependent anion transporter cell membrane molecules. These key proteins are responsible for tr... Read full blog post.