SR-BI Products

Antibodies
SR-BI Antibody
SR-BI Antibody
Species: Hu, Mu, Rt, ChHa, Ha, Md, Pm, Rb, SyHa
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Host: Rabbit Polyclonal
SR-BI Antibody
SR-BI Antibody
NB400-101
Species: Hu, Mu, Rt, Bv, ChHa, Md, Pm, Sj
Applications: WB, Simple Western, B/N, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Host: Rabbit Polyclonal
SR-BI Antibody
SR-BI Antibody
NB400-113
Species: Hu, Mu, Rt
Applications: WB, B/N, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Host: Rabbit Polyclonal
Antibody Packs
SR-BI Antibody Pack
SR-BI Antibody Pack
NB100-908
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IP
Lysates
SR-BI Overexpression Lysate ( ...
SR-BI Overexpression Lysate (Native)
NBL1-15720
Applications: WB
Proteins
SR-BI Peptide
SR-BI Peptide
NB400-131PEP
Species: Mu
SR-BI Peptide
SR-BI Peptide
NB400-101PEP
Species: Mu
Recombinant Human SR-BI Prote ...
Recombinant Human SR-BI Protein
H00000949-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
SR-BI RNAi
SR-BI RNAi
H00000949-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI--also known as Scavenger receptor class B, type I--binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Mouse
Rat
Product By Gene ID 949
Alternate Names
  • SR-B1
  • MGC138242
  • SCARB1
  • CD36 antigen
  • Collagen type I receptor, thrombospondin receptor-like 1
  • scavenger receptor class B type III
  • CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1
  • CD36L1scavenger receptor class B type 1
  • SRB1 scavenger receptor class B member 1
  • SRBI
  • CLA-1 HDLQTL6
  • CLA1 CD36 antigen-like 1
  • CD36 and LIMPII analogous 1
  • scavenger receptor class B, member 1

Research Areas for SR-BI

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Cholesterol Metabolism
Lipid and Metabolism
Signal Transduction

Bioinformatics Tool for SR-BI

Discover related pathways, diseases and genes to SR-BI. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related SR-BI Blog Posts

Check out the latest blog posts on SR-BI.
ABCA1 (ATP-binding cassette transporter A1)
The ABCA1 molecule is a primary gatekeeper for regulating the intracellular transport of cholesterol. It belongs to a larger related multifamily of cAMP-dependent anion transporter cell membrane molecules. These key proteins are responsible for tr...    Read more.
ABCA1 - The Caretaker for Cholesterol Transportation
The ATP-binding cassette transporter A1 (ABCA1) protein is a key gatekeeper for regulating intracellular cholesterol transport. It is one member of a large family of genes comprised of cAMP-dependent anion transporter cell membrane proteins. These imp...    Read more.
Scavenger's Helper - SR-BI (scavenger receptor class B member 1, SCARB1)
SR-B1 belongs to the CD36 scavenger receptor family and serves as a receptor for several ligands including phospholipids, cholesterol ester, lipoproteins, phosphatidylserine, and caveolae localized HDL. It is expressed in endothelial cells, macrophage...    Read more.
Read more SR-BI related blogs.