LIMPII/SR-B2 Products

Antibodies
LIMPII/SR-B2 Antibody
LIMPII/SR-B2 Antibody
NB400-102
Species: Hu, Mu, Rt, Bv, ChHa, Ha, Md
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
LIMPII/SR-B2 Antibody
LIMPII/SR-B2 Antibody
NBP1-77326
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-Fr, IHC-P, IF
Host: Rabbit Polyclonal
LIMPII/SR-B2 Antibody [Unconj ...
LIMPII/SR-B2 Antibody [Unconjugated]
AF1888
Species: Mu
Applications: WB, ICFlow
Host: Goat Polyclonal
Lysates
LIMPII/SR-B2 Overexpression L ...
LIMPII/SR-B2 Overexpression Lysate...
NBP2-04294
Applications: WB
LIMPII/SR-B2 Overexpression L ...
LIMPII/SR-B2 Overexpression Lysate...
H00000950-T01
Applications: WB
Proteins
LIMPII/SR-B2 Peptide
LIMPII/SR-B2 Peptide
NB400-102PEP
Species: Mu
LIMPII/SR-B2 Partial Recombin ...
LIMPII/SR-B2 Partial Recombinant P...
H00000950-Q01
Species: Hu
Applications: WB, ELISA, PA
LIMPII/SR-B2 Recombinant Prot ...
LIMPII/SR-B2 Recombinant Protein
H00000950-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
LIMPII/SR-B2 RNAi
LIMPII/SR-B2 RNAi
H00000950-R02
Species: Hu

Description

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII differs from SR-BI in that the encoded c-terminal cytoplasmic domain is almost completely different. SR-BII binds HDLs and mediates selective uptake of HDL cholesteryl ester, but with an approximately 4-fold lower efficiency than SR-BI. Nuclease protection assays show SR-BII to be abundant in mouse tissues expressing SR-BI, with SR-BII expression found in liver, adrenal glands, and testes. Although the role of SR-BII is not completely clear, research suggests that it may be a functional HDL receptor. In addition, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with the SR-BII isoform mediating selective transfer of lipid between HDL and cells. The relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Mouse
Product By Gene ID 950
Alternate Names
  • Scavenger receptor class B member 2,85 kDa lysosomal membrane sialoglycoprotein
  • Lysosome membrane protein II
  • CD36 antigen
  • CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2(lysosomal integral membrane protein II)
  • lysosome membrane protein 2
  • SR-BII
  • LIMP-2,85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2
  • AMRF
  • HLGP85
  • CD36L2LIMP II
  • LIMPIICD36 antigen-like 2
  • LGP85
  • scavenger receptor class B, member 2

Research Areas for LIMPII/SR-B2

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
Cholesterol Metabolism
GPCR
Lipid and Metabolism
Lysosome Markers
Neuronal Cell Markers
Neuroscience
Neurotransmission
Signal Transduction

PTMs for LIMPII/SR-B2

Learn more about PTMs related to LIMPII/SR-B2.

Glycosylation
Phosphorylation
Biotinylation
Cleavage

Bioinformatics Tool for LIMPII/SR-B2

Discover related pathways, diseases and genes to LIMPII/SR-B2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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