Spectrin beta 2 Antibody


Western Blot: Spectrin beta 2 Antibody [NBP1-01012] - Analysis of Spectrin Beta II pAb in extracts from COLO cells.

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Spectrin beta 2 Antibody Summary

Synthetic peptide, corresponding to amino acids 650-700 of Human Spectrin beta II.
Immunogen affinity purified
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  • Western Blot 1:500-1:1000
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analysis of Spectrin Beta II (M687) pAb in extracts from COLO cells.
Theoretical MW
275 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Positive Control
Spectrin beta 2 Lysate (NBP2-65527)

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
0.05% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for Spectrin beta 2 Antibody

  • beta-fodrin
  • beta-G spectrin
  • Beta-II spectrin
  • beta-spectrin 2
  • beta-spectrin II
  • betaSpII
  • ELF
  • embryonic liver beta-fodrin
  • Fodrin beta chain
  • spectrin beta chain, brain 1
  • spectrin, beta, non-erythrocytic 1
  • Spectrin, non-erythroid beta chain 1
  • SPTB2


SPTBN1 is a major constituent of the erythrocyte skeleton, accounting for 25% of the total membrane protein and 75% of the cytoskeletal mass. It is associated with the cytoplasmic surface of the membrane by attachment to ankyrin, a peripheral membrane protein. The membrane skeleton influences several cellular properties such as cell shape, restriction of mobility of the integral membrane protein exposed at the cell surface, and transmembrane movement of phospholipids and cholesterol. While the simplest form of SPTBN1 in solution is an alpha-beta heterodimer, SPTBN1 can undergo self-association in various conditions to form a tetramer of alpha2-beta2. In recent years a large number of SPTBN1-like molecules have been found in non-erythroid cells. These proteins are known by such different names as fodrin, CBP I, calspectin and TW 260/240.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

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Gene Symbol SPTBN1