SOX11 Antibody (CL0143) - BSA Free

Western Blot: SOX11 Antibody (CL0143) [NBP2-52865] - Lane 1: Marker [kDa], Lane 2: Negative control (vector only transfected HEK293T lysate), Lane 3: SOX11 Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells)

Immunohistochemistry-Paraffin: SOX11 Antibody (CL0143) [NBP2-52865] - Staining of human chronic lymphocytic leukemia shows no nuclear positivity in tumor cells as expected.

Immunohistochemistry-Paraffin: SOX11 Antibody (CL0143) [NBP2-52865] - Staining of human mantle cell lymphoma shows moderate to strong nuclear positivity in tumor cells.

• Reactivity: Hu
• Applications: WB, IHC
• Clone: CL0143
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

SOX11 Antibody (CL0143) - BSA Free Summary

• Description: Novus Biologicals Mouse SOX11 Antibody (CL0143) - BSA Free (NBP2-52865) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed using a recombinant protein derived from P35716, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: SOX11
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 1 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  SOX11 Recombinant Protein Antigen (NBP2-52865PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (82%), Rat (82%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Protein A purified

Alternate Names for SOX11 Antibody (CL0143) - BSA Free

• SOX11
• SRY (sex determining region Y)-box 11
• SRY (sex-determining region Y)-box 11
• SRY-related HMG-box gene 11
• transcription factor SOX-11

Background

SOX11 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SOX11