SOX1 Antibody [Unconjugated]


Western blot shows lysates of undifferentiated iBJ6 human iPS cells and iBJ6 human iPS cells differentiated into neuroprogenitor cells. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse/Rat SOX1 more
SOX1 was detected in immersion fixed BG01V human embryonic stem cells differentiated into neural progenitor cells using Goat Anti-Human/Mouse/Rat SOX1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3369) at more
SOX1 was detected in immersion fixed NTera‑2 human testicular embryonic carcinoma cell line differentiated with retinoic acid using Goat Anti-Human/Mouse/Rat SOX1 Antigen Affinity-purified Polyclonal Antibody (Catalog more
SOX1 was detected in immersion fixed rat cortical stem cells (Catalog # NSC001) using Goat Anti-Human/Mouse/Rat SOX1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3369) at 10 µg/mL for 3 hours at room more
SOX1 was detected in immersion fixed mouse cortical stem cells (Catalog # NSC002) using Goat Anti-Human/Mouse/Rat SOX1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3369) at 10 µg/mL for 3 hours at room more
SOX1 was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using Goat Anti-Human/Mouse/Rat SOX1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3369) at 3 µg/mL for 1 more
Simple Western lane view shows lysates of undifferentiated iBJ6 human iPS cells andiBJ6 human iPS cells differentiated into neuroprogenitor cells, loaded at 0.2 mg/mL. A specific band was detected for SOX1 at more

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Simple Western, IHC, ICC/IF

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SOX1 Antibody [Unconjugated] Summary

E. coli-derived recombinant human SOX1
Asn242-Gly379 (Leu276Ile)
Accession # NP_005977
Detects human SOX1 in direct ELISAs and Western blots.
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Immunocytochemistry 5-15 ug/mL
  • Immunohistochemistry 3-15 ug/mL
  • Simple Western 10 ug/mL
  • Western Blot 1 ug/mL
Read Publications using
AF3369 in the following applications:

Packaging, Storage & Formulations

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
No Preservative
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SOX1 Antibody [Unconjugated]

  • SOX1
  • SRY (sex determining region Y)-box 1
  • SRY-related HMG-box gene 1
  • transcription factor SOX-1


SOX1 is a 39 kDa transcription factor that belongs to the SOXB1 subgroup. Within the developing CNS, SOX1 maintains neural cells in an undifferentiated state and has been used as a marker for neural stem cells. Human and mouse SOX1 share 97% amino acid sequence identity.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SOX1 Antibody (AF3369)(62)

We have publications tested in 5 confirmed species: Human, Mouse, Rat, Primate (Macaca fascicularis), Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque).

We have publications tested in 5 applications: ICC, IHC, IHC-Fr, IHC-P, Western Blot.

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Primate (Macaca fascicularis)
Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
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Showing Publications 1 - 10 of 62. Show All 62 Publications.
Publications using AF3369 Applications Species
Chang, SY;Wu, TH;Shih, YL;Chen, YC;Su, HY;Chian, CF;Lin, YW; SOX1 Functions as a Tumor Suppressor by Repressing HES1 in Lung Cancer Cancers 2023-04-08 [PMID: 37190139] (ICC, Western Blot, Human) ICC, Western Blot Human
J Sidhaye, P Trepte, N Sepke, M Novatchkov, M Schutzbier, G Dürnberger, K Mechtler, JA Knoblich Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids Elife, 2023-03-29;12(0):. 2023-03-29 [PMID: 36989136] (IHC, Mouse) IHC Mouse
JT Czerminski, OD King, JB Lawrence Large-scale organoid study suggests effects of trisomy 21 on early fetal neurodevelopment are more subtle than variability between isogenic lines and experiments Frontiers in Neuroscience, 2023-02-03;16(0):972201. 2023-02-03 [PMID: 36817096] (IHC, Human) IHC Human
J Sun, S Osenberg, A Irwin, LH Ma, N Lee, Y Xiang, F Li, YW Wan, IH Park, M Maletic-Sa, N Ballas Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation Cell Reports, 2023-01-05;42(1):111942. 2023-01-05 [PMID: 36640327] (IHC, Human) IHC Human
R Yelagandul, K Stecher, M Novatchkov, L Michetti, G Michlits, J Wang, P Hofbauer, G Vainorius, C Pribitzer, L Isbel, S Mendjan, D Schübeler, U Elling, J Brennecke, O Bell ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers Nature Cell Biology, 2023-01-05;0(0):. 2023-01-05 [PMID: 36604593] (ICC, Mouse) ICC Mouse
L Li, X Si, J Yang, M Lei, H Liu, J Ruan, H Fu, W Li, H Yang, X Lei, H Sang Generation of a human iPSC line (CIBi014-A) from a patient with Parkinson's disease carrying a novel heterozygotic PARK8 (LRRK2) mutation Stem Cell Research, 2022-12-09;66(0):102995. 2022-12-09 [PMID: 36528012] (ICC, Human) ICC Human
MV Brady, J Mariani, Y Koca, A Szekely, RA King, MH Bloch, A Landeros-W, JF Leckman, FM Vaccarino Mispatterning and interneuron deficit in Tourette Syndrome basal ganglia organoids Molecular Psychiatry, 2022-11-29;0(0):. 2022-11-29 [PMID: 36447010] (IHC, Human) IHC Human
H Lin, SQ Ye, ZH Xu, JS Penaloza, M Aljuhani, T Vetter, MT Zhao, KL McBride Generation and characterization of a human induced pluripotent stem cell (iPSC) line from a patient with congenital heart disease (CHD) Stem Cell Research, 2022-10-31;65(0):102958. 2022-10-31 [PMID: 36343514] (ICC, Human) ICC Human
Y Zheng, CM Gallegos, H Xue, S Li, DH Kim, H Zhou, X Xia, Y Liu, Q Cao Transplantation of Human Induced Pluripotent Stem Cell-Derived Neural Progenitor Cells Promotes Forelimb Functional Recovery after Cervical Spinal Cord Injury Cells, 2022-09-05;11(17):. 2022-09-05 [PMID: 36078173] (ICC, Human) ICC Human
M Rhinn, I Zapata-Bod, A Klein, JL Plassat, T Knauer-Mey, WM Keyes Aberrant induction of p19Arf-mediated cellular senescence contributes to neurodevelopmental defects PloS Biology, 2022-06-14;20(6):e3001664. 2022-06-14 [PMID: 35700169] (IHC, Human) IHC Human
Show All 62 Publications.

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Deriving neural precursor cells from human induced pluripotent stem cells
By Jennifer Sokolowski, MD, PhD.Human induced pluripotent stem cells (iPSCs) can be used to create models of human organ systems and are useful for a) ascertaining the mechanisms underlying pathological conditions...  Read full blog post.

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Gene Symbol SOX1