SOX1 Antibody [Unconjugated]


Western blot shows lysates of undifferentiated iBJ6 human iPS cells and iBJ6 human iPS cells differentiated into neuroprogenitor cells. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse/Rat SOX1 more
Simple Western lane view shows lysates of undifferentiated iBJ6 human iPS cells andiBJ6 human iPS cells differentiated into neuroprogenitor cells, loaded at 0.2 mg/mL. A specific band was detected for SOX1 at more
SOX1 was detected in immersion fixed rat cortical stem cells (Catalog # NSC001) using Goat Anti-Human/Mouse/Rat SOX1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3369) at 10 µg/mL for 3 hours at room more
SOX1 was detected in immersion fixed mouse cortical stem cells (Catalog # NSC002) using Goat Anti-Human/Mouse/Rat SOX1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3369) at 10 µg/mL for 3 hours at room more
SOX1 was detected in immersion fixed BG01V human embryonic stem cells differentiated into neural progenitor cells using Goat Anti-Human/Mouse/Rat SOX1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3369) at more
SOX1 was detected in immersion fixed NTera‑2 human testicular embryonic carcinoma cell line differentiated with retinoic acid using Goat Anti-Human/Mouse/Rat SOX1 Antigen Affinity-purified Polyclonal Antibody (Catalog more

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Simple Western, IHC, ICC/IF

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SOX1 Antibody [Unconjugated] Summary

E. coli-derived recombinant human SOX1
Asn242-Gly379 (Leu276Ile)
Accession # NP_005977
Detects human SOX1 in direct ELISAs and Western blots. In direct ELISAs, less than 15% cross-reactivity with recombinant human (rh) SOX2 is observed.
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Immunocytochemistry 5-15 ug/mL
  • Immunohistochemistry 3-15 ug/mL
  • Simple Western 10 ug/mL
  • Western Blot 1 ug/mL
Read Publications using
AF3369 in the following applications:

Packaging, Storage & Formulations

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
No Preservative
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SOX1 Antibody [Unconjugated]

  • SOX1
  • SRY (sex determining region Y)-box 1
  • SRY-related HMG-box gene 1
  • transcription factor SOX-1


SOX1 is a 39 kDa transcription factor that belongs to the SOXB1 subgroup. Within the developing CNS, SOX1 maintains neural cells in an undifferentiated state and has been used as a marker for neural stem cells. Human and mouse SOX1 share 97% amino acid sequence identity.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SOX1 Antibody (AF3369)(44)

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque).

We have publications tested in 5 applications: ICC, IHC, IHC-Fr, IHC-P, Western Blot.

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Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
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Showing Publications 1 - 10 of 44. Show All 44 Publications.
Publications using AF3369 Applications Species
DM Dykxhoorn, X Tong, NC Gosstola, XZ Liu Derivation of iPSC line UMi029-A bearing a hearing-loss associated variant in the SMPX gene Stem Cell Research, 2021;54(0):102405. 2021 [PMID: 34052664] (ICC, Human) ICC Human
KP Kim, C Li, D Bunina, HW Jeong, J Ghelman, J Yoon, B Shin, H Park, DW Han, JB Zaugg, J Kim, T Kuhlmann, RH Adams, KM Noh, SA Goldman, HR Schöler Donor cell memory confers a metastable state of directly converted cells Cell Stem Cell, 2021;0(0):. 2021 [PMID: 33848472] (ICC, Mouse) ICC Mouse
V Krenn, C Bosone, TR Burkard, J Spanier, U Kalinke, A Calistri, C Salata, R Rilo Chris, P Pestana Ga, A Mirazimi, JA Knoblich Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly Cell Stem Cell, 2021;0(0):. 2021 [PMID: 33838105] (IHC, Human) IHC Human
C Gong, X Zheng, F Guo, Y Wang, S Zhang, J Chen, X Sun, SZA Shah, Y Zheng, X Li, Y Yin, Q Li, X Huang, T Guo, X Han, SC Zhang, W Wang, H Chen Human spinal GABA neurons alleviate spasticity and improve locomotion in rats with spinal cord injury Cell Reports, 2021;34(12):108889. 2021 [PMID: 33761348] (IHC, Rat) IHC Rat
T Malankhano, L Suldina, E Grigor'eva, S Medvedev, J Minina, K Morozova, E Kiseleva, S Zakian, A Malakhova A Human Induced Pluripotent Stem Cell-Derived Isogenic Model of Huntington's Disease Based on Neuronal Cells Has Several Relevant Phenotypic Abnormalities J Pers Med, 2020;10(4):. 2020 [PMID: 33182269] (ICC, Human) ICC Human
A Lundin, MJ Porritt, H Jaiswal, F Seeliger, C Johansson, AW Bidar, L Badertsche, S Wimberger, EJ Davies, E Hardaker, CP Martins, E James, T Admyre, A Taheri-Gha, J Bradley, A Schantz, B Alaeimahab, M Clausen, X Xu, LM Mayr, R Nitsch, M Bohlooly-Y, ST Barry, M Maresca Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery Nat Commun, 2020;11(1):4903. 2020 [PMID: 32994412] (ICC, Human) ICC Human
JM Dias, Z Alekseenko, A Jeggari, M Boareto, J Vollmer, M Kozhevniko, H Wang, MP Matise, A Alexeyenko, D Iber, J Ericson A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells Science Advances, 2020;6(38):. 2020 [PMID: 32938678] (ICC, Mouse) ICC Mouse
K Hirata, T Nambara, K Kawatani, N Nawa, H Yoshimatsu, H Kusakabe, K Banno, K Nishimura, M Ohtaka, M Nakanishi, H Taniguchi, H Arahori, K Wada, K Ozono, Y Kitabatake 4-Phenylbutyrate ameliorates apoptotic neural cell death in Down syndrome by reducing protein aggregates Sci Rep, 2020;10(1):14047. 2020 [PMID: 32820178] (ICC, Human) ICC Human
V Meraviglia, CH Arendzen, M Tok, C Freund, AS Maione, E Sommariva, M Bellin Generation of human induced pluripotent stem cell line LUMCi027-A and its isogenic gene-corrected line from a patient affected by arrhythmogenic cardiomyopathy and carrying the c.2013delC PKP2 mutation Stem Cell Res, 2020;46(0):101835. 2020 [PMID: 32485643] (ICC, Human) ICC Human
V Meraviglia, CH Arendzen, C Freund, DE Atsma, CL Mummery, M Bellin Generation of two human induced pluripotent stem cell lines, LUMCi020-A and LUMCi021-A, from two patients with Catecholaminergic Polymorphic Ventricular Tachycardia carrying heterozygous mutations in the RYR2 gene Stem Cell Res, 2020;45(0):101764. 2020 [PMID: 32315959] (ICC, Human) ICC Human
Show All 44 Publications.

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Blogs on SOX1.

Deriving neural precursor cells from human induced pluripotent stem cells
By Jennifer Sokolowski, MD, PhD.Human induced pluripotent stem cells (iPSCs) can be used to create models of human organ systems and are useful for a) ascertaining the mechanisms underlying pathological conditions...  Read full blog post.

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Gene Symbol SOX1